Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| A061402 | Alliance | Solitary Plasmacytoma of Bone: Randomized Phase III Trial to Evaluate Treatment with Adjuvant Systemic Treatment and Zoledronic Acid Versus Zoledronic Acid After Definite Radiation Therapy | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A062101 | Alliance | A Phase I/II Study of the Safety, Tolerability and Efficacy of Belantamab Mafodotin (GSK2857916) in Combination with Iberdomide (CC-220)/Dexamethasone versus Belantamab Mafodotin (GSK2857916)/Dexamethasone in Relapsed Refractory Multiple Myeloma | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A062102 | Alliance | Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A071102 | Alliance | A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A071401 | Alliance | Phase II Trial of SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas with SMO/AKT/NF2/CDK Pathway Mutations | Adult CIRB - Early Phase Emphasis | Available to Open | |
| A071601 | Alliance | Phase II Trial of BRAF/MEK Inhibitors in Papillary Craniopharyngiomas | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A071701 | Alliance | Genomically-Guided Treatment Trial in Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A071702 | Alliance | A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A071801 | Alliance | Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS) for Resected Metastatic Brain Disease | Adult CIRB - Late Phase Emphasis | Available to Open | |
| A072201 | Alliance | Randomized Phase II Trial of Anti-Lag-3 and Anti-PD-1 Blockade vs. SOC in Patients with Recurrent Glioblastoma | Adult CIRB - Late Phase Emphasis | Available to Open |