CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
A211701 Alliance A Prospective Study to Establish a New Onset Hyperglycemia and Diabetes (NOD) Cohort Cancer Prevention and Control CIRB Completed
A211801 Alliance BRCA-P: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, International Phase 3 Study to Determine the Preventive Effect of Denosumab on Breast Cancer in Women Carrying a BRCA1 Germline Mutation Cancer Prevention and Control CIRB Available to Open
A211901 Alliance Reaching Rural Cancer Survivors Who Smoke Using Text-Based Cessation Interventions Cancer Prevention and Control CIRB Available to Open
A212102 Alliance Blinded Reference Set for Multicancer Early Detection Blood Tests Cancer Prevention and Control CIRB Available to Open
A221208 Alliance Randomized Phase II Study: Corticosteroids and Bevacizumab vs. Corticosteroids and Placebo (BeSt) for Radionecrosis after Radiosurgery for Brain Metastases Cancer Prevention and Control CIRB Available to Open
A221405 Alliance A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women with Endocrine Responsive Breast Cancer who Desire Pregnancy Cancer Prevention and Control CIRB Available to Open
A221504 Alliance A Randomized, Double-Blind, Placebo-Controlled Pilot Study of an Oral, Selective Peripheral Opioid Receptor Antagonist in Advanced Non-Small Cell Lung Cancer Cancer Prevention and Control CIRB Available to Open
A221505 Alliance RT Charm: Phase III Randomized Trial of Hypofractionated Post Mastectomy Radiation with Breast Reconstruction Cancer Prevention and Control CIRB Available to Open
A221602 Alliance Olanzapine with or without fosaprepitant for the prevention of chemotherapy induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC): A Phase III Randomized, Double Blind, Placebo-Controlled Trial Cancer Prevention and Control CIRB Available to Open
A221701 Alliance Phase III Placebo-Controlled Trial to Evaluate Dexamethasone Use for Everolimus-Induced Oral Stomatitis: Prevention Versus Early Treatment Approaches: MIST (My Individualized Stomatitis Treatment) Cancer Prevention and Control CIRB Completed