CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
A071601 Alliance Phase II Trial of BRAF/MEK Inhibitors in Papillary Craniopharyngiomas Adult CIRB - Late Phase Emphasis Available to Open
A071701 Alliance Genomically-Guided Treatment Trial in Brain Metastases Adult CIRB - Late Phase Emphasis Available to Open
A071702 Alliance A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma Adult CIRB - Late Phase Emphasis Available to Open
A071801 Alliance Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS) for Resected Metastatic Brain Disease Adult CIRB - Late Phase Emphasis Available to Open
A081105 Alliance Randomized Study of Erlotinib Vs Observation in Patients with Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC) Adult CIRB - Late Phase Emphasis Available to Open
A081801 Alliance Integration of Immunotherapy into Adjuvant Therapy for Resected NSCLC: ALCHEMIST Chemo-IO Adult CIRB - Late Phase Emphasis Available to Open
A082002 Alliance A Randomized Phase II/III Trial of Modern Immunotherapy Based Systemic Therapy with or without SBRT for PD-L1-Negative, Advanced Non-small Cell Lung Cancer Adult CIRB - Late Phase Emphasis Available to Open
A082101 Alliance Multimodality Therapy with Immunotherapy in Stage I-IIIA Sarcomatoid Mesothelioma Adult CIRB - Late Phase Emphasis Available to Open
A091105 Alliance A Phase III; Double Blind; Randomized; Placebo-Controlled Trial of Sorafenib in Desmoid Tumors or Aggressive Fibromatosis (DT/DF) Adult CIRB - Late Phase Emphasis Available to Open
A091202 Alliance A Phase II Study of the Peroxisome Proliferator-Activated Receptor Gamma
Agonist; Efatutazone in Patients with Previously Treated; Unresectable Myxoid Liposarcoma
Adult CIRB - Early Phase Emphasis Available to Open