CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
MDA20-01-01 CP-CTNet_CLO-MD Anderson A Phase IIa, Placebo-Controlled, Randomized Study of Daily Obeticholic Acid (OCA) to Reduce Intestinal Polyp Burden in Familial Adenomatous Polyposis (FAP) Cancer Prevention and Control CIRB
MDA20-02-01 CP-CTNet_CLO-MD Anderson Time Restricted Eating And Metformin (TEAM) in Invasive Breast Cancer (IBC) or Ductal Carcinoma in Situ (DCIS). A randomized, Phase IIb, Window of Opportunity Presurgical Trial. Cancer Prevention and Control CIRB
MDA2013-02-02 CP-CTNet_CLO-MD Anderson Effect of Aspirin on Biomarkers of Barrett’s Esophagus After Successful Eradication of Barrett’s Esophagus with Radiofrequency Ablation Cancer Prevention and Control CIRB
MDA2014-04-01 CP-CTNet_CLO-MD Anderson Alternative Dosing of Exemestane in Postmenopausal Women with Stage 0-II ER-Positive Breast Cancer: a Randomized Presurgical Trial Cancer Prevention and Control CIRB
MDA2014-04-02 CP-CTNet_CLO-MD Anderson VADIS Trial: Phase II trial of Nelipepimut-S Peptide Vaccine in Women with DCIS of the Breast Cancer Prevention and Control CIRB
MDA2016-07-02 CP-CTNet_CLO-MD Anderson A Randomized, Double-blind, Placebo-controlled Study of 4-hydroxytamoxifen Topical Gel in Women with Mammographically Dense Breast Cancer Prevention and Control CIRB
MDA2016-08-02 CP-CTNet_CLO-MD Anderson A Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer Cancer Prevention and Control CIRB
MDA2017-09-03 CP-CTNet_CLO-MD Anderson Pilot Study of Denosumab in BRCA1/2 Mutation Carriers scheduled for Risk-reducing Salpingooophorectomy Cancer Prevention and Control CIRB
MDA21-06-01 CP-CTNet_CLO-MD Anderson A Phase Ib/II Clinical Trial of Nous-209 for Recurrent Neoantigen Immunogenicity and Cancer Immune Interception in Lynch Syndrome Cancer Prevention and Control CIRB
MM1MDS-A01 Alliance A Randomized Phase II Trial of Enasidenib-Based Therapies Versus Cedazuridine-Decitabine in Higher-Risk IDH2-Mutated Myelodysplastic Syndrome: A MyeloMATCH Sub-Study Adult CIRB - Late Phase Emphasis