Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| 9706 | ETCTN | Randomized phase II study to assess the role of Nivolumab as single agent to eliminate minimal residual disease and maintain remission in acute myelogenous leukemia (AML) patients after chemotherapy (REMAIN Trial) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9742 | ETCTN | Multicenter Phase II Study of Nivolumab in Previously Treated Patients with Recurrent and Metastatic Nasopharyngeal Carcinoma | Adult CIRB - Early Phase Emphasis | Completed | |
| 9767 | ETCTN | An Open Label; Multicenter; Single arm Phase II study to evaluate the Activity and Tolerability of the novel mTOR Inhibitor; MLN0128 (TAK-228); in patients with Locally Advanced or Metastatic Transitional Cell Carcinoma of the urothelial tract whose tumors harbor a TSC1 and/or a TSC2 mutation | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9775 | ETCTN | A Phase 2 Study of MLN0128 (TAK-228) in Relapsed and/or Refractory Acute Lymphoblastic Leukemia (ALL) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9782 | ETCTN | A Phase 1 Study of Talazoparib (BMN 673) in Combination with Carboplatin and Paclitaxel in Patients with Advanced Solid Tumors | Adult CIRB - Early Phase Emphasis | Completed | |
| 9824 | ETCTN | A Phase 1 Study of alisertib (MLN8237) in combination with mFOLFOX in gastrointestinal tumors | Adult CIRB - Early Phase Emphasis | Completed | |
| 9825 | ETCTN | A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9837 | ETCTN | Phase I Study of TRC102 in Combination with Cisplatin and Pemetrexed in Patients with Advanced Solid Tumors / Phase II Study of TRC102 with Pemetrexed in Patients Refractory to Pemetrexed and Cisplatin or Carboplatin | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9844 | ETCTN | A Phase 1 Study Evaluating Safety; Tolerability; and Preliminary Antitumor Activity of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 9846 | ETCTN | Patient-Derived Models Tissue Procurement Protocol For The National Cancer Institute (NCI) | Adult CIRB - Early Phase Emphasis | Available to Open |