NSABP-B-52
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NSABP
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A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients with Hormone Receptor-Positive; HER2-Positive; Large Operable and Locally Advanced Breast Cancer Treated with Neoadjuvant Therapy of Docetaxel; Carboplatin; Trastuzumab; and Pertuzumab (TCHP) With or Without Estrogen Deprivation
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Adult CIRB - Late Phase Emphasis
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Completed
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NSABP-B-55
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NSABP
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A Randomised; Double-blind; Parallel group; Placebo-controlled Multi-centre Phase III Study to Assess the Efficacy and Safety of Olaparib Versus Placebo as Adjuvant Treatment in Patients with Germline BRCA1/2 mutations and High Risk HER2 Negative Primary Breast Cancer Who Have Completed Definitive Local Treatment and Neoadjuvant or Adjuvant Chemotherapy
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NSABP-C-08
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NSABP
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A Phase III Clinical Trial Comparing Infusional 5-Fluorouracil (5-FU); Leucovorin; and Oxaliplatin (mFOLFOX6) Every Two Weeks with Bevacizumab to the Same Regimen without Bevacizumab for the Treatment of Patients with Resected Stages II and III Carcinoma of the Colon
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Adult CIRB - Late Phase Emphasis
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Completed
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NSABP-C-09
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NSABP
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A Phase III Clinical Trial Comparing Oxaliplatin; Capecitabine; and Hepatic Arterial Infusion of Floxuridine to Oxaliplatin and Capecitabine in Patients with Resected or Ablated Liver Metastases from Colorectal Cancer.
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Adult CIRB - Late Phase Emphasis
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Completed
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NSABP-C-11
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NSABP
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A Phase III Study Evaluating the Role of Perioperative Chemotherapy in Patients with Potentially Resectable Hepatic Colorectal Metastases
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Adult CIRB - Late Phase Emphasis
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Completed
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NSABP-NCIC-CTG-MA.32.F
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NSABP
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Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NSABP-R-04
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NSABP
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A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with or without Oxaliplatin with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-Fluorouracil with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma of the Rectum
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Adult CIRB - Late Phase Emphasis
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Completed
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NWU20-01-03
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CLO-Northwestern University
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Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD): RELIEF-NAFLD
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Cancer Prevention and Control CIRB
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Available to Open
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NWU20-02-01
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CLO-Northwestern University
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Surgical Window of Opportunity Study of Megestrol Acetate Compared with Megestrol Acetate and Metformin for Endometrial Intraepithelial Neoplasia
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Cancer Prevention and Control CIRB
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Available to Open
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NWU20-02-02
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CLO-Northwestern University
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A Randomized and Placebo-Controlled Phase II Trial Targeting Dominant-Negative Missense Mutant P53 By Atorvastatin for Reducing the Risk of Longstanding Ulcerative Colitis-Associated Cancer
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Cancer Prevention and Control CIRB
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Available to Open
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