NRG-GY024
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NRG
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Groningen International Study on Sentinel Nodes in Vulvar Cancer (GROINSS-V) III: A Prospective Phase II Treatment Trial
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY025
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NRG
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A Randomized Phase II Trial of Nivolumab and Ipilimumab Compared to Nivolumab Monotherapy in Patients with Deficient Mismatch Repair System Recurrent Endometrial Carcinoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY026
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NRG
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A Phase II/III Study of Paclitaxel/Carboplatin Alone or Combined with Either Trastuzumab and Hyaluronidase-oysk (HERCEPTIN HYLECTA) or Pertuzumab, Trastuzumab, and Hyaluronidase-zzfx (PHESGO) in HER2 Positive, Stage I-IV Endometrial Serous Carcinoma or Carcinosarcoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY027
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NRG
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Phase I/IB Safety and Pharmacodynamic Study of Neoadjuvant (NACT) Paclitaxel and Carboplatin with Ipatasertib as Initial Therapy of Ovarian Cancer PTMA 100805
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY028
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NRG
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A Phase IB and Randomized Phase II Trial of Megestrol Acetate with or without Ipatasertib in Recurrent or Metastatic Endometrioid Endometrial Cancer
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY029
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NRG
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A Randomized Phase II Trial Comparing the Combination of PI3K Inhibitor Copanlisib (BAY 80-6946) and PARP Inhibitor Olaparib (AZD2281) to Standard Chemotherapy in Patients with Recurrent Platinum Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer who have Progressed through Prior PARP Inhibitor Therapy
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY031
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NRG
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A Phase 1B Study of Combination ATR (M1774) and BET Inhibition (ZEN00-3694) to Exploit ARID1A Loss in Recurrent Ovarian and Endometrial Cancer
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY032
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NRG
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A Phase II Study of Tailored Adjuvant Therapy in Pole-Mutated and p53-Wildtype/NSMP Early-Stage Endometrial Cancer (RAINBO BLUE & TAPER)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-GY033
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NRG
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A Phase II Study of Androgen Receptor (AR) Inhibition by Darolutamide in Combination with Leuprolide Acetate and Exemestane in Recurrent Adult-Type Ovarian Granulosa Cell Tumor
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Adult CIRB - Late Phase Emphasis
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Available to Open
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NRG-HN001
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RTOG
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Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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