EA6183
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ECOG-ACRIN
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A Phase II Neoadjuvant Study of Encorafenib with Binimetinib in Patients with Resectable Locoregional Metastases from Cutaneous or Unknown Primary Melanoma (Stages III N1B/C/D)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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EA6191
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ECOG-ACRIN
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The BAMM2 (BRAF, Autophagy, MEK inhibition in Melanoma) Study: A Randomized Double Blind Phase II Study of Dabrafenib and Trametinib with or without Hydroxychloroquine in Advanced BRAF V600E/K Melanoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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EA6192
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ECOG-ACRIN
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A Phase II Study of Biomarker Driven Early Discontinuation of Anti-PD-1 Therapy in Patients with Advanced Melanoma (PET-Stop)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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EA6194
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ECOG-ACRIN
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Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination with CMP-001 in Patients with Operable Melanoma: Efficacy and Biomarker Study
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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EA7211
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ECOG-ACRIN
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A Randomized Phase III Study of Neoadjuvant Chemotherapy followed by Surgery versus Surgery Alone for Patients with High Risk RetroPeritoneal Sarcoma (STRASS 2)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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EA7222
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ECOG-ACRIN
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A Randomized Phase III Trial of Doxorubicin + Pembrolizumab Versus Doxorubicin Alone for the Treatment of Undifferentiated Pleomorphic Sarcoma (UPS) and Related Poorly Differentiated Sarcomas
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Adult CIRB - Late Phase Emphasis
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Available to Open
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EA8134
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ECOG-ACRIN
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InPACT- International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study)
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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EA8141
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ECOG-ACRIN
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A Prospective Phase II Trial of Neoadjuvant Systemic Chemotherapy followed by Extirpative Surgery for Patients with High Grade Upper Tract Urothelial Carcinoma
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Adult CIRB - Late Phase Emphasis
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Completed
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EA8143
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ECOG-ACRIN
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A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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EA8153
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ECOG-ACRIN
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Cabazitaxel with Abiraterone versus Abiraterone alone Randomized Trial for Extensive Disease following Docetaxel: the CHAARTED2 Trial
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Adult CIRB - Late Phase Emphasis
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Available to Open
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