Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| 10150 | ETCTN | A randomized phase 2 study of bevacizumab and either weekly anetumab ravtansine or weekly paclitaxel in platinum-resistant or platinum refractory ovarian cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10166 | ETCTN | A Phase 2 Study of Atezolizumab and Cobimetinib in PD-1/PD-L1 Inhibitor Resistant or Refractory Non-Small Cell Lung Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10170 | ETCTN | A Phase 2 Study of AZD1775 in SETD2-Deficient Advanced Solid Tumor Malignancies | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10181 | ETCTN | A Phase 2 Study of Savolitinib in Subjects with MET Amplified Metastatic Colorectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10183 | ETCTN | A Pilot Study of Tazemetostat and MK-3475 (Pembrolizumab) in Advanced Urothelial Carcinoma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10184 | ETCTN | Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10186 | ETCTN | A Phase I/II Study of Nivolumab plus or minus Ipilimumab in Combination with Multi-fraction Stereotactic Radiosurgery for Recurrent High-grade Radiation-relapsed Meningioma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10191 | ETCTN | A Phase 2 Study of M6620 in Combination with Carboplatin compared with Docetaxel in Combination with Carboplatin in Metastatic Castration-Resistant Prostate Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10193 | ETCTN | Phase 2 Study of Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-cell Lymphoma and Primary Mediastinal Large B-cell Lymphoma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10195 | ETCTN | A Phase 2 Study of Copanlisib (BAY 80-6946) in Combination with Fulvestrant in Women with Metastatic Breast Cancer Progressing After Aromatase Inhibitor Plus CDK 4/6 Inhibitor | Adult CIRB - Early Phase Emphasis | Completed |