CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
10147 ETCTN A Phase II randomized study of topotecan/carboplatin with or without veliparib in advanced myeloproliferative disorders and chronic myelomonocytic leukemia (CMML). Adult CIRB - Early Phase Emphasis
10150 ETCTN A randomized phase 2 study of bevacizumab and either weekly anetumab ravtansine or weekly paclitaxel in platinum-resistant or platinum refractory ovarian cancer Adult CIRB - Early Phase Emphasis
10166 ETCTN A Phase 2 Study of Atezolizumab and Cobimetinib in PD-1/PD-L1 Inhibitor Resistant or Refractory Non-Small Cell Lung Cancer Adult CIRB - Early Phase Emphasis
10170 ETCTN A Phase 2 Study of AZD1775 in SETD2-Deficient Advanced Solid Tumor Malignancies Adult CIRB - Early Phase Emphasis
10181 ETCTN A Phase 2 Study of Savolitinib in Subjects with MET Amplified Metastatic Colorectal Cancer Adult CIRB - Early Phase Emphasis
10183 ETCTN A Pilot Study of Tazemetostat and MK-3475 (Pembrolizumab) in Advanced Urothelial Carcinoma Adult CIRB - Early Phase Emphasis
10184 ETCTN Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) Adult CIRB - Early Phase Emphasis
10186 ETCTN A Phase I/II Study of Nivolumab plus or minus Ipilimumab in Combination with Multi-fraction Stereotactic Radiosurgery for Recurrent High-grade Radiation-relapsed Meningioma Adult CIRB - Early Phase Emphasis
10191 ETCTN A Phase 2 Study of M6620 in Combination with Carboplatin compared with Docetaxel in Combination with Carboplatin in Metastatic Castration-Resistant Prostate Cancer Adult CIRB - Early Phase Emphasis
10193 ETCTN Phase 2 Study of Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-cell Lymphoma and Primary Mediastinal Large B-cell Lymphoma Adult CIRB - Early Phase Emphasis