Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| 10483 | ETCTN | Phase Ib trial of Erdafitinib combined with Enfortumab Vedotin following platinum and PD1/L1 inhibitors for metastatic urothelial carcinoma with FGFR2/3 genetic alterations | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10486 | ETCTN | Phase 2 Trial of the Combination of the BET inhibitor, ZEN003694 (ZEN-3694), and the PARP Inhibitor Talazoparib, in Patients with Molecularly-Selected Solid Tumors (ComBET) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10487 | ETCTN | A Phase II study of Lutetium Lu 177 dotatate in metastatic prostate cancer with neuroendocrine differentiation | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10490 | ETCTN | Rapid Analysis and Response Evaluation of Combination Anti-neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 2 Talazoparib and Temozolomide | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10492 | ETCTN | Phase 1/1b Study of AKT Inhibitor Ipatasertib with Chemoradiation for Locally Advanced Head and Neck Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10495 | ETCTN | Phase I Trial of DS-8201a (Trastuzumab Deruxtecan) in Combination with Neratinib in Solid Tumors with HER2 Alterations | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10496 | ETCTN | A Phase 2 Study of Ipatasertib in Combination with Pembrolizumab for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10499 | ETCTN | Phase Ib/II study of ZEN003694 and entinostat in advanced and refractory solid tumors and lymphomas | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10500 | ETCTN | Phase 1/Expansion Study of Tazemetostat Plus Belinostat for the Treatment of Relapsed or Refractory Lymphoma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10504 | ETCTN | A Randomized Phase 2 Study of Atezolizumab with or without Selinexor in Alveolar Soft Part Sarcoma (AXIOM) | Adult CIRB - Early Phase Emphasis | Available to Open |