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    • Our Mission
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      • Adult CIRB - Late Phase Emphasis Members
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    • CIRB SOPs
    • List of Institutions
    • Studies
  • For New Users
    • Overview of the Study Review Process
    • Frequently Asked Questions about Navigating IRBManager
    • When To Use NCI CIRB, IRBManager, and CTSU Websites
  • For Institutions
    • IRBManager Basics
    • Overview of the Study Review Process
    • Becoming A Signatory Institution
    • Navigating The CIRB For NCI Division of Cancer Prevention (DCP) Consortia Sites And Cancer Prevention Clinical Trial Network (CP-CTNET) Organizations
    • Create and Update the Signatory Institution Worksheet
      • Completing The Annual Signatory Institution Worksheet
      • Establishing Your Signatory Institution
      • Short Form Q & A
    • Creating and Updating the Annual Principal Investigator Worksheet
      • Establishing a Principal Investigator
    • How to Open a Study
      • Opening a Study
    • Change the PI on a Study
      • Changing the PI on a Study
    • Submit a Study Closure
    • Report A Potential Unanticipated Problem Or A Serious Or Continuing Noncompliance
    • Request an Assent Waiver
      • Completing The Assent Waiver Worksheet
    • Notify the CIRB about the participation of an incarcerated participant
      • Completing The Notification of Incarcerated Participant Worksheet
      • Institution Q & A
      • Boilerplate Language Q & A
      • Finding Information Q & A
      • Guidelines For Permitted Boilerplate Language Additions
      • Individual Roles Within The CIRB
      • Institutions' Roles With The CIRB
      • Managing Your CTEP Registration
      • Oversight Q & A
      • Updating Your CIRB Institution Roster using RUMS
      • Updating Your CIRB Person Roster using RUMS
      • Viewing Your CIRB Roster
  • For Networks
    • Overview of the Study Review Process
    • CIRB Document Posting
    • Submitting Studies
      • Completing The Translation Application
      • Completing The Unanticipated Problem And/Or Serious or Continuing Noncompliance Submission Application
      • Completing The Waiver Of Consent Application
      • Completing the Amendment Review Application
      • Completing the Continuing Review Application
      • Completing the Initial Review Application
      • Determining Waiver Of Consent Requirements
      • End User Licensing Agreement (Eula) Consent Form Language Q & A
      • Review of Translated Consent Forms, PROs, and Other Patient-Facing Documents
      • Submitting Recruitment/participant Materials For Review
    • CIRB Meeting Schedules
  • For Board Members
    • Become A Board Member
    • Overview of the Study Review Process
    • Resources
      • Helpful URLs
      • IRBManager Training for Board Members
    • CIRB Meeting Schedules
  • Contact Us

AA Watermark

  • Read more about AA Watermark

NRG Study Closure Confirmation Form

  • Read more about NRG Study Closure Confirmation Form

Alliance Study Closure Confirmation Form

  • Read more about Alliance Study Closure Confirmation Form

Application for Translation Review

  • Read more about Application for Translation Review

Amendment Review Application

  • Read more about Amendment Review Application

Study Closure Confirmation Form

  • Read more about Study Closure Confirmation Form

New Early Study Closure Confirmation Form

  • Read more about New Early Study Closure Confirmation Form

IRBManager Help

  • Read more about IRBManager Help
  • NCI CIRB Helpdesk

CIRB Website Help

  • Read more about CIRB Website Help
  • NCI CIRB Helpdesk

IRBManager Roles and Resources

  • Read more about IRBManager Roles and Resources
  • For Local Context staff, IRBManager houses all the Local Context Worksheets you’ll need. These include:
    • Annual Signatory Institution and Annual PI Worksheets
    • Study-Specific, Change of PI, and Study Closure Worksheets
    • Unanticipated Problem and/or Noncompliance Worksheet
    • Requesting an Assent Waiver Worksheet
    • Notification of Incarcerated Participant Worksheet
  • For the Network Group staff, IRBManager is where you'll complete the Continuing Review Applications for studies covered by the CIRB.

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The NCI Central Institutional Review Board

401 N. Washington Street, Ste. 700
Rockville, MD 20850

The Central Institutional Review Board for the National Cancer of Institute is fully accredited by the Association for the Accreditation of Human Research Protection Program, Inc.