CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website. 

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Lead Group Study Title CIRB Study Status
ARAR0332 COG Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy: A Groupwide Phase III Study Pediatric CIRB Available to Open
ARAR2221 COG Phase 2 Study Using Chemoimmunotherapy with Gemcitabine, Cisplatin and Nivolumab in Newly Diagnosed Nasopharyngeal Carcinoma (NPC) Pediatric CIRB Available to Open
AREN0321 COG Treatment of High Risk Renal Tumors: A Groupwide Phase II Study Pediatric CIRB Completed
AREN03B2 COG Renal Tumors Classification; Biology; and Banking Study Pediatric CIRB Available to Open
AREN0532 COG Treatment for Very Low and Standard Risk Favorable Histology Wilms Tumor: A Groupwide Phase III Study Pediatric CIRB Available to Open
AREN0533 COG Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors: A Groupwide Phase III Study Pediatric CIRB Available to Open
AREN0534 COG Treatment for Patients with Bilateral; Multicentric; or Bilaterally-Predisposed Unilateral Wilms Tumor: A Groupwide Phase III Study Pediatric CIRB Available to Open
AREN1721 COG A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Axitinib or Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups Pediatric CIRB Available to Open
AREN1921 COG Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT) Pediatric CIRB Available to Open
ARET0231 COG A Single Arm Trial of Systemic and Subtenon Chemotherapy for Groups C and D Intraocular Retinoblastoma Pediatric CIRB Completed