Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| ABTC-1701 | ABTC | Pilot Surgical PK Study of BGB324 in Recurrent Glioblastoma Patients | Adult CIRB - Early Phase Emphasis | Available to Open | |
| ABTC-1801 | ABTC | Phase I/II Study of Pamiparib (BGB-290) with Temozolomide in Recurrent Gliomas with IDH1/2 Mutations | Adult CIRB - Early Phase Emphasis | Available to Open | |
| ABTC-1802 | ABTC | A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor | Adult CIRB - Late Phase Emphasis | Available to Open | |
| ABTC-1804 | ABTC | Determining the Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients with Gliomas | Adult CIRB - Late Phase Emphasis | Available to Open | |
| ABTR04B1 | COG | Establishing Continuous Cell Lines and Xenografts from Pediatric Cancers for Biological and Pre-Clinical Therapeutic Studies | Pediatric CIRB | Available to Open | |
| ACCL0431 | COG | A Randomized Phase III Study of Sodium Thiosulfate (IND#72877; NSC#45624) for the Prevention of Cisplatin-Induced Ototoxicity in Children: A Groupwide Phase III Study | Pediatric CIRB | Completed | |
| ACCL04C2 | COG | Randomized Study of Electroacupuncture Treatment for Delayed Chemotherapy-induced Nausea and Vomiting in Patients with Pediatric Solid Tumors 02-AT-0172 | Pediatric CIRB | Completed | |
| ACCL05C1 | COG | A Group-Wide; Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy | Pediatric CIRB | Completed | |
| ACCL0631 | COG | Impact of Obesity on the Pharmacokinetics of Anticancer Therapy in Children with High Risk Acute Lymphoblastic Leukemia (ALL): A Group-wide Non-Therapeutic Study | Pediatric CIRB | Completed | |
| ACCL0933 | COG | A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML): A Groupwide Phase III Study | Pediatric CIRB | Completed |