S1403
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SWOG
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A Randomized Phase II Trial of Afatinib Plus Cetuximab Versus Afatinib Alone in Treatment-Naive Patients with Advanced, EGFR Mutation Positive Non-Small Cell Lung Cancer (NSCLC) (BI 1200.124)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1404
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SWOG
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A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose Interferon or Ipilimumab to MK-3475 (Pembrolizumab) in Patients with High Risk Resected Melanoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1406
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SWOG
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Randomized Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
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Adult CIRB - Early Phase Emphasis
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Available to Open
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S1416
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SWOG
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Phase II Randomized Placebo-Controlled Trial of Cisplatin with or without ABT-888 (Veliparib) in Metastatic Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast Cancer with or Without Brain Metastases
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1418
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SWOG
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A Randomized; Phase III Trial to Evaluate the Efficacy and Safety of MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast Cancer with >/=1 cm Residual Invasive Cancer or Positive Lymph Nodes (ypN+) after Neoadjuvant Chemotherapy
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1500
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SWOG
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A Randomized; Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968]; Crizotinib [NSC #749005]; Savolitinib [NSC #785348]; and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1501
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SWOG
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Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer; Phase III
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Cancer Prevention and Control CIRB
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Available to Open
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S1505
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SWOG
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A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/NAB-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1507
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SWOG
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A Phase II Trial of Trametinib with Docetaxel in Patients with Kras Mutation Positive Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease Following One or Two Prior Systemic Therapies
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1512
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SWOG
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A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unresectable Desmoplastic Melanoma (DM)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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