CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
N1048 NCCTG N1048 (PROSPECT**): A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision Adult CIRB - Late Phase Emphasis
N107C NCCTG A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease Adult CIRB - Late Phase Emphasis
NCCTG-N06C6 NCCTG A Phase III Randomized Trial of Cryoablation vs. Radiation for the Palliation of Painful Bone Metastases Adult CIRB - Late Phase Emphasis
NCIC-BR.19 NCIC CTG A Phase III Prospective Randomized; Double-Blind; Placebo-Controlled Trial of the Epidermal Growth Factor Receptor Antagonist; ZD1839 (IRESSA) in Completely Resected Primary Stage IB; II and IIIA Non-Small Cell Lung Cancer Adult CIRB - Late Phase Emphasis
NCIC-MA.27 NCIC CTG A Randomized Phase III Trial of Exemestane Versus Anastrozole in PostMenopausal Women With Receptor Positive Primary Breast Cancer Adult CIRB - Late Phase Emphasis
NCIC-MA.27B NCIC CTG The Influence of Five Years of Adjuvant Anastrozole or Exemestane on bone Mineral Density in Postmenopausal Women with Primary Breast Cancer - A Companion Study to NCIC CTG MA.27 Adult CIRB - Late Phase Emphasis
NCIC-MA.32 NCIC CTG A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer Adult CIRB - Late Phase Emphasis
NCIC-PR.11 NCIC CTG A Phase III Study of Active Surveillance Therapy Against Radical Treatment in Patients Diagnosed With Favourable Risk Prostate Cancer (START) Adult CIRB - Late Phase Emphasis
NCICOVID NCI NCI COVID-19 in Cancer Patients Study (N-CCaPS): A Longitudinal Natural History Study Adult CIRB - Late Phase Emphasis
NHLBI-MDS ECOG The National Myelodysplastic Syndromes (MDS) Study Cancer Prevention and Control CIRB