Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| EA2174 | ECOG-ACRIN | A Phase II/III Study of Peri-operative Nivolumab and Ipilimumab in Patients with Locoregional Esophageal and Gastroesophageal Junction Adenocarcinoma | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2176 | ECOG-ACRIN | A Randomized Phase III Study of Immune Checkpoint Inhibition with Chemotherapy in Treatment-Naïve Metastatic Anal Cancer Patients | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2182 | ECOG-ACRIN | A Randomized Phase II Study of De-Intensified ChemoRadiation for Early-Stage Anal Squamous Cell Carcinoma (DECREASE) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2183 | ECOG-ACRIN | A Phase III Study of Consolidative Radiotherapy in Patients with Oligometastatic HER2 Negative Esophageal and Gastric Adenocarcinoma (EGA) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2185 | ECOG-ACRIN | Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs | Cancer Prevention and Control CIRB | Available to Open | |
| EA2186 | ECOG-ACRIN | A Randomized Phase II Study of Gemcitabine and Nab-Paclitaxel Compared with 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan in Older Patients with Treatment Naïve Metastatic Pancreatic Cancer (GIANT) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2187 | ECOG-ACRIN | A Phase 2 Study of Pevonedistat in Combination with Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2192 | ECOG-ACRIN | APOLLO: A Randomized Phase II Double-Blind Study of Olaparib versus Placebo Following Adjuvant Chemotherapy in Patients with Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2197 | ECOG-ACRIN | Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA2201 | ECOG-ACRIN | A Phase II Study of Neoadjuvant Nivolumab plus Ipilimumab and Short-Course Radiation in MSI-H/dMMR Locally Advanced Rectal Adenocarcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |