CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
EA1131 ECOG-ACRIN A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Breast Cancer following Neoadjuvant Chemotherapy Adult CIRB - Late Phase Emphasis Available to Open
EA1141 ECOG-ACRIN Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis in Breast Cancer Screening in Women with Dense Breasts Cancer Prevention and Control CIRB Completed
EA1151 ECOG-ACRIN Tomosynthesis Mammographic Imaging Screening Trial (TMIST) Cancer Prevention and Control CIRB Available to Open
EA1181 ECOG-ACRIN (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response Adult CIRB - Late Phase Emphasis Available to Open
EA1183 ECOG-ACRIN FDG PET to Assess Therapeutic Response in Patients with Bone-dominant Metastatic Breast Cancer, FEATURE Adult CIRB - Late Phase Emphasis Available to Open
EA1211 ECOG-ACRIN Interim FDG-PET/CT for PreDIcting REsponse of HER2+ Breast Cancer to Neoadjuvant Therapy: DIRECT trial Adult CIRB - Late Phase Emphasis Available to Open
EA2131 ECOG-ACRIN A Phase I and Randomized Phase II Study of Nab-Paclitaxel/Gemcitabine with or without AZD1775 for Treatment of Metastatic Adenocarcinoma of the Pancreas Adult CIRB - Early Phase Emphasis Available to Open
EA2142 ECOG-ACRIN Randomized Phase II Study of Platinum and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Tumors including Poorly Differentiated Neuroendocrine Carcinomas and Well-Differentiated Neuroendocrine Neoplasms Adult CIRB - Early Phase Emphasis Available to Open
EA2161 ECOG-ACRIN A Phase II Study of MLN0128 (TAK-228) in Rapalog-Resistant Advanced Pancreatic Neuroendocrine Tumors (PNET) Adult CIRB - Late Phase Emphasis Available to Open
EA2165 ECOG-ACRIN A Randomized Phase II Study of Nivolumab After Combined Modality Therapy (CMT) in High Risk Anal Cancer Adult CIRB - Late Phase Emphasis Available to Open