CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
CALGB-90601 CALGB A Randomized Double-Blinded Phase III Study Comparing Gemcitabine; Cisplatin; and Bevacizumab to Gemcitabine; Cisplatin; and Placebo in Patients with Advanced Transitional Cell Carcinoma Adult CIRB - Late Phase Emphasis
CALGB-90802 CALGB Randomized Phase III Trial Comparing Everolimus Versus Everolimus Plus Bevacizumab for Advanced Renal Cell Carcinoma Progressing After Treatment with Tyrosine Kinase Inhibitors Adult CIRB - Late Phase Emphasis
CCTG CE.7 NCIC CTG A Phase III Trial of Stereotactic Radiosurgery Compared with Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5-15 Brain Metastases Adult CIRB - Late Phase Emphasis
CCTG MA.39 NCIC CTG Tailor RT: A Randomized Trial of Regional Radiotherapy in Biomarker Low Risk Node Positive Breast Cancer Adult CIRB - Late Phase Emphasis
CCTG-BR38 CCTG Consolidative Use of Radiotherapy to Block (CURB2) Oligoprogression in Patients with Metastatic Non-Small-Cell Lung Cancer - A Randomized Phase 3 Trial Adult CIRB - Late Phase Emphasis
CCTG-CO32 CCTG The NEO-RT Trial: A Phase 3 Randomized Trial of Neoadjuvant Chemotherapy, Excision and Observation versus ChemoRadioTherapy for Early Rectal Cancer Adult CIRB - Late Phase Emphasis
CCTG-HN11 NCIC CTG SPECT-CT Guided Elective Contralateral Neck Treatment (Select) for Patients with Lateralized Oropharyngeal Cancer: A Phase III Randomized Controlled Trial Adult CIRB - Late Phase Emphasis
CCTG-NE1 CCTG NET RETREAT: A Phase II Study of 177 Lutetium-DOTATATE Retreatment vs. Everolimus in Metastatic/Unresectable Midgut NET Adult CIRB - Late Phase Emphasis
CCTG-PR24 CCTG Androgen Suppression Combined with Elective Nodal Irradiation and Dose Escalated Prostate Treatment: A Non-Inferiority, Phase III Randomized Controlled Trial of Stereotactic Body Radiation Therapy versus Brachytherapy Boost in Patients with Unfavourable Risk Localized Prostate Cancer (ASCENDE SBRT) Adult CIRB - Late Phase Emphasis
CCTG-PR26 CCTG A Randomized Phase III Clinical Trial for the Addition of Docetaxel to Androgen Receptor Pathway Inhibitors in Patients with Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response (TRIPLE-SWITCH) Adult CIRB - Late Phase Emphasis