CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
ANBL00B1 COG Neuroblastoma Biology Studies Pediatric CIRB
ANBL00P3 COG A Phase III Randomized Trial of Intravenous Gammaglobulin Therapy for Patients with Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated with Chemotherapy and Prednisone Pediatric CIRB
ANBL0322 COG A Phase II Study of hu14.18-IL2*(BB-IND-9798) In Children with Recurrent or Refractory Neuroblastoma Pediatric CIRB
ANBL0421 COG A Phase II Study of Irinotecan + Temozolomide in Children with Recurrent Neuroblastoma: A Groupwide Phase II Study Pediatric CIRB
ANBL0531 COG Response- and Biology-Based Therapy for Intermediate-risk Neuroblastoma: A Groupwide Phase III Study Pediatric CIRB
ANBL0532 COG Phase III Randomized Trial of Single vs. Tandem Myeloablative Consolidation Therapy for High-Risk Neuroblastoma: A Groupwide Phase III Study Pediatric CIRB
ANBL0931 COG A Comprehensive Safety Trial of Chimeric Antibody 14.18 (ch14.18) with GM-CSF, IL-2 and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy Pediatric CIRB
ANBL09P1 COG A COG Pilot Study of Intensive Induction Chemotherapy and 131I-MIBG Followed by Myeloablative Busulfan/Melphalan (Bu/Mel) for Newly Diagnosed High-Risk Neuroblastoma: A Limited Institution Pilot Study Pediatric CIRB
ANBL1021 COG Feasibility/Phase II Study of hu14.18-IL2 immunocytokine + GM-CSF and Isotretinoin in Patients with Relapsed or Refractory Neuroblastoma: A Groupwide Phase II Study Pediatric CIRB
ANBL1221 COG A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864; IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 764038; IND# 4308) in Children with Refractory; Relapsed or Progressive Neuroblastoma Pediatric CIRB