CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
ACCL16N1CD COG Documentation and Delivery of Guideline-Consistent Treatment in Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL) Pediatric CIRB
ACCL1931 COG A Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy Pediatric CIRB
ACCL1932 COG Letermovir Prophylaxis for Cytomegalovirus in Pediatric Hematopoietic Cell Transplantation Pediatric CIRB
ACCL2031 COG A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors Pediatric CIRB
ACCL20N1CD COG Financial Distress during Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States Pediatric CIRB
ACCL21C2 COG Prospective Cohort Study to Evaluate Immunologic Response Following COVID-19 Vaccination in Children, Adolescents and Young Adults with Cancer Pediatric CIRB
ACCL2433 COG Risk-Based 6MP Adherence Enhancement Strategies in Children, Adolescent and Young Adults with ALL – A Pilot Study Pediatric CIRB
ACCRN07 COG Protocol for the Enrollment on the Official COG Registry; The Childhood Cancer Research Network (CCRN) Pediatric CIRB
ACNS0221 COG A Phase II Study of Conformal Radiotherapy In Patients with Low-Grade Gliomas Pediatric CIRB
ACNS0222 COG A Phase II Study of Motexafin-Gadolinium (NSC #695238; IND #55583) and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Groupwide Phase II Study Pediatric CIRB