Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| 10605 | ETCTN | A Phase 1 Study of ZEN003694 (ZEN-3694) in Combination with Cetuximab and Encorafenib in Patients with Refractory BRAF V600E Metastatic Colorectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10608 | ETCTN | A Phase II Trial of Durvalumab with Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma | Adult CIRB - Early Phase Emphasis | Completed | |
| 10612 | ETCTN | A Randomized Phase 2 Study of Daratumumab-Selinexor-Velcade-Dexamethasone (Dara-SVD) for High-Risk Newly Diagnosed Multiple Myeloma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10614 | ETCTN | A Phase 1/2 Study of Nivolumab and Ipilimumab in Combination with Sirolimus and Prednisone in Kidney Transplant Recipients with Selected Unresectable or Metastatic Cutaneous Cancers | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10620 | ETCTN | A Phase 1b Trial of Teclistamab in Combination with Iberdomide for Relapsed/Refractory Multiple Myeloma | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10629 | ETCTN | A Phase I Dose Finding and Phase II Randomized Trial of Iadademstat Combined with Immune Checkpoint Inhibition Maintenance After Initial Chemoimmunotherapy in Patients with Extensive-Stage Small Cell Lung Cancer | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10630 | ETCTN | Phase 1 Trial of Iadademstat in Combination with Venetoclax and Azacitidine in Patients with Treatment Naive AML | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10637 | ETCTN | A Phase 2 Study of Venetoclax in Relapsed Classic or Variant Hairy Cell Leukemia | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 10647 | ETCTN | Phase I/Ib Study of Eribulin in Combination with ASTX660 (tolinapant) in Metastatic Triple Negative Breast Cancer (TNBC) | Adult CIRB - Early Phase Emphasis | Available to Open | |
| 8329 | ETCTN | A Phase I/II Trial of ABT-888, an Inhibitor of Poly(ADP-ribose) Polymerase (PARP), and Topotecan (TPT) in Patients with Solid Tumors (Phase I) and Relapsed Ovarian Cancer or Primary Peritoneal Cancer (Phase II) After Prior Platinum Containing First-Line Chemotherapy | Adult CIRB - Early Phase Emphasis | Available to Open |