S1925
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SWOG
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Randomized, Phase II Study of Early Intervention with Venetoclax and Obinutuzumab versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): EVOLVE CLL/SLL Study
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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S1929
|
SWOG
|
Phase II Randomized Study of Maintenance Atezolizumab Versus Atezolizumab in Combination with Talazoparib in Patients with SLFN11 Positive Extensive Stage Small Cell Lung Cancer (ES-SCLC)
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
|
S1931
|
SWOG
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Phase III Trial Of Immunotherapy-Based Combination Therapy With Or Without Cytoreductive Nephrectomy For Metastatic Renal Cell Carcinoma (Probe Trial)
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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S1933
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SWOG
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A Pilot Study of Hypofractionated Radiotherapy Followed by Atezolizumab Consolidation in Stage II or III NSCLC Patients with Borderline Performance Status
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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S1934
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SWOG
|
NASSIST (Neoadjuvant Chemoradiation +/- Immunotherapy Before Surgery for Superior Sulcus Tumors): A Randomized Phase II Trial of Trimodality +/- Atezolizumab in Resectable Superior Sulcus Non-Small Cell Lung Cancer
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
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S1937
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SWOG
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A Phase III Randomized Trial of Eribulin (NSC #707389) with or without Gemcitabine versus Standard of Care (Physician's Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible for, Anti PD1/PDL1 Therapy
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
|
S2000
|
SWOG
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A Randomized Phase 2 Trial of Encorafenib + Binimetinib + Nivolumab vs Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma with Brain Metastases
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
|
S2001
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SWOG
|
Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients with Germline BRCA1 or BRCA2 Mutations
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
|
S2005
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SWOG
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A Phase II Randomized Study of Ibrutinib and Rituximab with or without Venetoclax in Previously Untreated Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)
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Adult CIRB - Late Phase Emphasis
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Available to Open
|
|
S2007
|
SWOG
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A Phase II Trial of Sacituzumab Govitecan (IMMU-132) (NSC #820016) for Patients with HER2-Negative Breast Cancer and Brain Metastases
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Adult CIRB - Late Phase Emphasis
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Available to Open
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