S1900E
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SWOG
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A Phase II Study of AMG 510 in Participants with Previously Treated Stage IV or Recurrent KRAS G12C Mutated Non-Squamous Non-Small Cell Lung Cancer (ECOG-ACRIN LungMAP Sub-Study)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1900F
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SWOG
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A Randomized Phase II Study of Carboplatin and Pemetrexed with or Without Selpercatinib (LY3527723) in Participants with Non-Squamous RET Fusion-Positive Stage IV Non-Small Cell Lung Cancer and Progression of Disease on Prior RET Directed Therapy (Lung-MAP Sub-Study)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1900G
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SWOG
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A Randomized Phase II Study of INC280 (capmatinib) plus Osimertinib with or without Ramucirumab in Participants with EGFR-Mutant, MET-Amplified Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1900K
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RTOG
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A Randomized Phase II Study of Tepotinib with or without Ramucirumab in Participants with MET Exon 14 Skipping Positive Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Sub-Study)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1904
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SWOG
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Cluster Randomized Controlled Trial of Patient and Provider Decision Support to Increase Chemoprevention Informed Choice Among Women with Atypical Hyperplasia or Lobular Carcinoma in Situ – Making Informed Choices On Incorporating Chemoprevention Into Care (MiCHOICE)
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Cancer Prevention and Control CIRB
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Available to Open
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S1905
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SWOG
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A Phase I/II Study of AKR1C3-Activated Prodrug OBI‐3424 (OBI-3424) in Patients with Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL)/T-Cell Lymphoblastic Lymphoma (T-LBL)
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1912CD
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SWOG
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A Randomized Trial Addressing Cancer-Related Financial Hardship Through Delivery of a Proactive Financial Navigation Intervention (CREDIT)
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Cancer Prevention and Control CIRB
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Available to Open
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S1914
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SWOG
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A Randomized Phase III Trial of Induction/Consolidation Atezolizumab (NSC #783608) + SBRT versus SBRT Alone in High Risk, Early Stage NSCLC
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1918
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SWOG
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A Phase II/III Randomized Study of R-miniCHOP with or without CC-486 (Oral Azacitidine) in Participants Age 75 Years or Older with Newly Diagnosed Diffuse Large B Cell Lymphoma, Grade IIIb Follicular Lymphoma, Transformed Lymphoma, and High-Grade B-Cell Lymphomas with MYC and BCL2 and/or BCL6 Rearrangements
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Adult CIRB - Late Phase Emphasis
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Available to Open
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S1922
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SWOG
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Randomized Phase II Selection Study of Ramucirumab and Paclitaxel Versus FOLFIRI In Refractory Small Bowel Adenocarcinoma
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Adult CIRB - Late Phase Emphasis
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Available to Open
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