CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
NCIC-MA.32 NCIC CTG A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer Adult CIRB - Late Phase Emphasis
NCIC-PR.11 NCIC CTG A Phase III Study of Active Surveillance Therapy Against Radical Treatment in Patients Diagnosed With Favourable Risk Prostate Cancer (START) Adult CIRB - Late Phase Emphasis
NCICOVID NCI NCI COVID-19 in Cancer Patients Study (N-CCaPS): A Longitudinal Natural History Study Adult CIRB - Late Phase Emphasis
NHLBI-MDS ECOG The National Myelodysplastic Syndromes (MDS) Study Cancer Prevention and Control CIRB
NHSR10.2021 NCI 21st Century Cures Act and PRA Implementation Adult CIRB - Late Phase Emphasis
NRG-BN001 NRG Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation With Concomitant and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma Adult CIRB - Late Phase Emphasis
NRG-BN002 NRG Phase I Study Of Ipilimumab; Nivolumab; And The Combination In Patients With Newly Diagnosed Glioblastoma Adult CIRB - Early Phase Emphasis
NRG-BN003 NRG Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma Adult CIRB - Late Phase Emphasis
NRG-BN005 NRG A Phase II Randomized Trial of Proton vs. Photon Therapy (IMRT) for Cognitive Preservation in Patients with IDH Mutant, Low to Intermediate Grade Gliomas Adult CIRB - Late Phase Emphasis
NRG-BN007 NRG A Randomized Phase II/III Open-Label Study of Ipilimumab and Nivolumab versus Temozolomide in Patients with Newly Diagnosed MGMT (Tumor O-6-Methylganine DNA Methyltransferase) Unmethylated Glioblastoma Adult CIRB - Late Phase Emphasis