CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
MyeloMATCH SWOG Master Screening and Reassessment Protocol (MSRP) for Tier Advancement in the NCI MyeloMATCH Clinical Trials Adult CIRB - Late Phase Emphasis
N0147 NCCTG A Randomized Phase III Trial of Oxaliplatin (OXAL) plus 5-Fluorouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225) after Curative Resection for Patients with Stage III Colon Cancer Adult CIRB - Late Phase Emphasis
N0434 (MA.27D) NCCTG The Association of Breast Density Changes; Plasma Hormone Changes; and<br>Breast Cancer Recurrence: A Companion Study to NCIC CTG MA.27 Adult CIRB - Late Phase Emphasis
N0574 NCCTG Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases Adult CIRB - Late Phase Emphasis
N0577 NCCTG N0577 (CODEL): Phase III Intergroup Study of Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q Co-deleted Anaplastic Glioma or Low Grade Glioma Adult CIRB - Late Phase Emphasis
N0723 NCCTG MARVEL: Marker Validation of Erlotinib in Lung Cancer- A Phase III Biomarker Validation Study of Second-line Therapy in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) Randomized to Pemetrexed Versus Erlotinib Adult CIRB - Late Phase Emphasis
N0949 NCCTG Randomized Phase III Trial of mFOLFOX7 or XELOX Plus Bevacizumab Versus 5-Fluorouracil/Leucovorin or Capecitabine Plus Bevacizumab as First-line Treatment in Elderly Patients with Metastatic Colorectal Cancer Adult CIRB - Late Phase Emphasis
N1048 NCCTG N1048 (PROSPECT**): A Phase II/III Trial of Neoadjuvant FOLFOX with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision Adult CIRB - Late Phase Emphasis
N107C NCCTG A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease Adult CIRB - Late Phase Emphasis
NCCTG-N06C6 NCCTG A Phase III Randomized Trial of Cryoablation vs. Radiation for the Palliation of Painful Bone Metastases Adult CIRB - Late Phase Emphasis