CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
GOG-0263 GOG Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk; Stage I/IIA Cervical Cancer Treated with Initial Radical Hysterectomy and Pelvic Lymphadenectomy Adult CIRB - Late Phase Emphasis
GOG-0275 GOG A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia Adult CIRB - Late Phase Emphasis
GOG-0277 GOG A Phase III Randomized Trial of Gemcitabine (NSC# 613327) Plus Docetaxel (NSC# 628503) Followed by Doxorubicin (NCS# 123127) versus Observation for Uterus-Limited; High Grade Uterine Leiomyosarcoma Adult CIRB - Late Phase Emphasis
GOG-0281 GOG A Randomized Phase II/III Study To Assess The Efficacy of Trametinib (GSK 1120212) In Patients With Recurrent Or Progressive Low-Grade Serous Ovarian Cancer Or Peritoneal Cancer. NCT # NCT02101788 Adult CIRB - Late Phase Emphasis
GOG-0286B GOG A Randomized Phase II/III Study Of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo As Initial Therapy For Measurable Stage III Or IVA; Stage IVB; or Recurrent Endometrial Cancer Adult CIRB - Late Phase Emphasis
INT21-05-01 CLO-Northwestern University Phase IIB Clinical Trial of the Multitargeted Recombinant Adenovirus 5 (CEA/MUC1/Brachyury) Vaccine (TRI-AD5) and IL-15 Superagonist N-803 in Lynch Syndrome Cancer Prevention and Control CIRB
INT22-09-01 CP-CTNet_CLO-University of Wisconsin A Randomized Trial of Apalutamide in Non-Muscle Invasive Bladder Cancer Cancer Prevention and Control CIRB
LungMAP SWOG A Master Protocol to Evaluate Biomarker-Driven Therapies and Immunotherapies in Previously-Treated Non-Small Cell Lung Cancer (Lung-MAP Screening Study) Adult CIRB - Late Phase Emphasis
MAY2015-05-01 CP-CTNet_CLO-Mayo Clinic Randomized, double-blind, placebo-controlled trial of Meriva® (curcuminoids) as a candidate chemoprevention agent for gastric carcinogenesis Cancer Prevention and Control CIRB
MAY2016-07-01 CP-CTNet_CLO-Mayo Clinic Phase II Trial of Weekly Erlotinib Dosing to Reduce Duodenal Polyp Burden Associated with Familial Adenomatous Polyposis Cancer Prevention and Control CIRB