CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
EAQ211 ECOG-ACRIN Social Genomic Mechanisms of Health Disparities among Adolescent and Young Adult (AYA) Survivors of Hodgkin and Non-Hodgkin Lymphoma Cancer Prevention and Control CIRB
EAQ221CD ECOG-ACRIN Improving Medication Adherence in Metastatic Breast Cancer using a CONnected CUstomized Treatment Platform (CONCURxP) Cancer Prevention and Control CIRB
EAQ222CD ECOG-ACRIN Effectiveness of Out-of-Pocket Cost COMmunication and Financial Navigation (CostCOM) in Cancer Patients Cancer Prevention and Control CIRB
EAQ223 ECOG-ACRIN The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials Cancer Prevention and Control CIRB
EAY131 ECOG-ACRIN Molecular Analysis for Therapy Choice (MATCH) Adult CIRB - Early Phase Emphasis
EAY191 ECOG-ACRIN Molecular Analysis for Combination Therapy Choice (ComboMATCH) Adult CIRB - Early Phase Emphasis
EAY191-A3 Alliance A ComboMATCH Treatment Trial: Palbociclib and Binimetinib in RAS-Mutant Cancers Adult CIRB - Early Phase Emphasis
EAY191-A6 ECOG-ACRIN A ComboMATCH Treatment Trial: FOLFOX in Combination with Binimetinib as 2nd Line Therapy for Patients with Advanced Biliary Tract Cancers with MAPK Pathway Alterations Adult CIRB - Early Phase Emphasis
EAY191-E4 ECOG-ACRIN A ComboMATCH Treatment Trial ComboMATCH Treatment Trial E4: Nilotinib and Paclitaxel in Patients with Prior Taxane-Treated Solid Tumors Adult CIRB - Early Phase Emphasis
EAY191-E5 ECOG-ACRIN A ComboMATCH Treatment Trial ComboMATCH Treatment Trial E5: A Randomized Phase II Study of AMG 510 (Sotorasib) with or without Panitumumab in Advanced Solid Tumors Adult CIRB - Early Phase Emphasis