CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
EAA181 ECOG-ACRIN Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase 3 Trial for Newly Diagnosed Multiple Myeloma Not Intended For Early Autologous Transplantation Adult CIRB - Late Phase Emphasis
EAA241 ECOG-ACRIN A Randomized Phase II Trial Comparing Daratumumab-Bortezomib-Dexamethasone versus Cyclophosphamide-Bortezomib-Dexamethasone in Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) Adult CIRB - Late Phase Emphasis
EAE161 ECOG-ACRIN Perfusion CT to Predict Progression-free Survival and Response Rate in Bevacizumab and Paclitaxel Treatment of Platinum-Resistant Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Peritoneal Carcinoma Adult CIRB - Late Phase Emphasis
EAF151 ECOG-ACRIN Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma Adult CIRB - Late Phase Emphasis
EAF223 ECOG-ACRIN Phase II Glioblastoma Accelerated Biomarkers Learning Environment Trial (GABLE) Adult CIRB - Late Phase Emphasis
EAQ152 ECOG-ACRIN A Randomized Study of Pre-disclosure Genetic Education v. Usual Care in Tumor Profiling for Advanced Cancer and a Pilot Study of Remote Genetic Counseling for Participants with Potential Germline Mutations Identified on Tumor Profiling Adult CIRB - Early Phase Emphasis
EAQ161CD ECOG-ACRIN Biomarker Testing in Common Solid Cancers: An Assessment of Current Practices in Precision Oncology in the Community Setting Cancer Prevention and Control CIRB
EAQ162CD ECOG-ACRIN Longitudinal Assessment of Financial Burden in Patients with Colon or Rectal Cancer Treated with Curative Intent Cancer Prevention and Control CIRB
EAQ171CD ECOG-ACRIN Implementing a Virtual Tobacco Treatment in Community Oncology Practices: “Smoke Free Support Study 2.0” Cancer Prevention and Control CIRB
EAQ172 ECOG-ACRIN Optimizing Immunosuppression for Steroid- Refractory Anti-PD-1/PD-L1 Pneumonitis Cancer Prevention and Control CIRB