CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
EAA171 ECOG-ACRIN Optimizing Prolonged Treatment In Myeloma Using MRD Assessment (OPTIMUM) Adult CIRB - Late Phase Emphasis Available to Open
EAA172 ECOG-ACRIN Phase 1/2 Study of Daratumumab, Bortezomib, Dexamethasone with or without Venetoclax in Relapsed/Refractory Multiple Myeloma with Assessment for t(11;14) Status Adult CIRB - Late Phase Emphasis Completed
EAA173 ECOG-ACRIN Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) Adult CIRB - Late Phase Emphasis Available to Open
EAA181 ECOG-ACRIN Effective Quadruplet Utilization After Treatment Evaluation (EQUATE): A Randomized Phase 3 Trial for Newly Diagnosed Multiple Myeloma Not Intended For Early Autologous Transplantation Adult CIRB - Late Phase Emphasis Available to Open
EAE161 ECOG-ACRIN Perfusion CT to Predict Progression-free Survival and Response Rate in Bevacizumab and Paclitaxel Treatment of Platinum-Resistant Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Peritoneal Carcinoma Adult CIRB - Late Phase Emphasis Completed
EAF151 ECOG-ACRIN Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma Adult CIRB - Late Phase Emphasis Available to Open
EAF223 ECOG-ACRIN Phase II Glioblastoma Accelerated Biomarkers Learning Environment Trial (GABLE) Adult CIRB - Late Phase Emphasis Available to Open
EAQ152 ECOG-ACRIN A Randomized Study of Pre-disclosure Genetic Education v. Usual Care in Tumor Profiling for Advanced Cancer and a Pilot Study of Remote Genetic Counseling for Participants with Potential Germline Mutations Identified on Tumor Profiling Adult CIRB - Early Phase Emphasis Completed
EAQ161CD ECOG-ACRIN Biomarker Testing in Common Solid Cancers: An Assessment of Current Practices in Precision Oncology in the Community Setting Cancer Prevention and Control CIRB Completed
EAQ162CD ECOG-ACRIN Longitudinal Assessment of Financial Burden in Patients with Colon or Rectal Cancer Treated with Curative Intent Cancer Prevention and Control CIRB Available to Open