Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| E5202 | ECOG | A Randomized Phase III Study Comparing 5-FU; Leucovorin and Oxaliplatin Versus 5-FU; Leucovorin; Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers | Adult CIRB - Late Phase Emphasis | Available to Open | |
| E5204 | ECOG | Intergroup Randomized Phase III Study of Postoperative Oxaliplatin; 5-Fluorouracil; and Leucovorin vs Oxaliplatin; 5-Fluorouracil; Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-Operative Chemoradiation | Adult CIRB - Late Phase Emphasis | Completed | |
| E5508 | ECOG | Randomized Phase III Study of Maintenance Therapy with Bevacizumab; Pemetrexed; or a Combination of Bevacizumab and Pemetrexed Following Carboplatin; Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open | |
| E6201 | ECOG | A Phase III; Randomized Study of Gemcitabine [fixed-dose rate infusion] and Oxaliplatin (NSC 266046) versus Gemcitabine [fixed-dose rate infusion] versus Gemcitabine [30-minute infusion] in Pancreatic Carcinoma | Adult CIRB - Late Phase Emphasis | Completed | |
| EA1131 | ECOG-ACRIN | A Randomized Phase III Post-Operative Trial of Platinum Based Chemotherapy Vs. Capecitabine in Patients with Residual Triple-Negative Breast Cancer following Neoadjuvant Chemotherapy | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA1141 | ECOG-ACRIN | Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis in Breast Cancer Screening in Women with Dense Breasts | Cancer Prevention and Control CIRB | Completed | |
| EA1151 | ECOG-ACRIN | Tomosynthesis Mammographic Imaging Screening Trial (TMIST) | Cancer Prevention and Control CIRB | Available to Open | |
| EA1181 | ECOG-ACRIN | (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA1183 | ECOG-ACRIN | FDG PET to Assess Therapeutic Response in Patients with Bone-dominant Metastatic Breast Cancer, FEATURE | Adult CIRB - Late Phase Emphasis | Available to Open | |
| EA1211 | ECOG-ACRIN | Interim FDG-PET/CT for PreDIcting REsponse of HER2+ Breast Cancer to Neoadjuvant Therapy: DIRECT trial | Adult CIRB - Late Phase Emphasis | Available to Open |