CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
AHOD1331 COG A Randomized Phase III Study of Brentuximab Vedotin (SGN-35; IND #117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents: A Groupwide Phase III Study Pediatric CIRB
AHOD2131 COG A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma Pediatric CIRB
ALTE03N1 COG Key Adverse Events after Childhood Cancer Pediatric CIRB
ALTE05N1 COG Umbrella Long-Term Follow-Up Protocol Pediatric CIRB
ALTE07C1 COG Neuropsychological; Social; Emotional; and Behavioral Outcomes in Children with Cancer: A Groupwide Non-Therapeutic Study Pediatric CIRB
ALTE11C1 COG Longitudinal Assessment of Ovarian Reserve in Adolescents with Lymphoma: A Groupwide Non-Therapeutic Protocol Pediatric CIRB
ALTE11C2 COG Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy: A Limited Institution Non-Therapeutic Study Pediatric CIRB
ALTE15N2 COG LEAHRN (Late Effects After High-Risk Neuroblastoma) Study Pediatric CIRB
ALTE1621 COG Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Heart Failure (PREVENT-HF): A Phase 2b Randomized Placebo-Controlled (Carvedilol) Trial Pediatric CIRB
ALTE1631 COG A Randomized Web-based Physical Activity Intervention among Children with Cancer Pediatric CIRB