CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Review CIRB
Study Status
Study Number Sort descending Lead Group Study Title CIRB Study Status
ACCL2031 COG A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors Pediatric CIRB Available to Open
ACCL20N1CD COG Financial Distress during Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States Pediatric CIRB Available to Open
ACCL21C2 COG Prospective Cohort Study to Evaluate Immunologic Response Following COVID-19 Vaccination in Children, Adolescents and Young Adults with Cancer Pediatric CIRB Completed
ACCL2433 COG Risk-Based 6MP Adherence Enhancement Strategies in Children, Adolescent and Young Adults with ALL – A Pilot Study Pediatric CIRB Available to Open
ACCRN07 COG Protocol for the Enrollment on the Official COG Registry; The Childhood Cancer Research Network (CCRN) Pediatric CIRB Available to Open
ACNS0221 COG A Phase II Study of Conformal Radiotherapy In Patients with Low-Grade Gliomas Pediatric CIRB Completed
ACNS0222 COG A Phase II Study of Motexafin-Gadolinium (NSC #695238; IND #55583) and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Groupwide Phase II Study Pediatric CIRB Completed
ACNS0224 COG A Phase I/II Study of Topotecan with G-CSF and Radiation Therapy In Children with Malignant Intrinsic Pontine Brainstem Gliomas of Childhood Pediatric CIRB Completed
ACNS0232 COG Radiotherapy Alone vs. Chemotherapy Followed by Response-based Radiotherapy for Newly Diagnosed Primary CNS Germinoma: A Phase III Group-Wide Study Pediatric CIRB Completed
ACNS0332 COG Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients: A Groupwide Phase III Study Pediatric CIRB Available to Open