CIRB Studies

Below is the current list of studies covered by the CIRB. Participants should refer to ClinicalTrials.gov for general information about clinical trials. Institutions should refer to the Clinical Trials Support Unit (CTSU) website  for enrollment requirements and accrual status information. 

Study documents approved after July 1, 2013 are available to participating institutions for covered studies on the CTSU website. To request documents approved before July 1, 2013, participating institutions can contact the CIRB Helpdesk.

Review CIRB
Study Number Network Study Title CIRB
ACCL0934 COG A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT): A Groupwide Phase III Study Pediatric CIRB
ACCL0935 COG Prevention of Cancer/Treatment-Related Weight Loss in Children at High Nutritional Risk Pediatric CIRB
ACCL1031 COG A Randomized Double Blinded Trial of Topical Caphosol to Prevent Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation: A Groupwide Phase III Study Pediatric CIRB
ACCL1032 COG A Randomized Controlled Trial of Acupressure to Control Chemotherapy-Induced Nausea (CIN) in Children Receiving Cisplatin: A Groupwide Phase III Study Pediatric CIRB
ACCL1033 COG A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL: A Group-wide Non-Therapeutic Study Pediatric CIRB
ACCL1034 COG Impact of Cleansing with Chlorhexidine Gluconate (CHG) on Reducing Central Line Associated Bloodstream Infection (CLABSI) and Acquisition of Multi-drug Resistant Organisms (MDRO) in Children with Cancer or Those Receiving Allogeneic Hematopoietic Cell Transplantation (HCT): A Limited Phase III Study Pediatric CIRB
ACCL10P1 COG Computerized Cognitive Training for Pediatric Brain Tumor Patients: A Pilot Study Pediatric CIRB
ACCL1131 COG A Phase III Open-Label Trial of Caspofungin vs. Azole Prophylaxis for Patients at High-Risk for Invasive Fungal Infections (IFI) Following Allogeneic Hematopoietic Cell Transplantation (HCT) Pediatric CIRB
ACCL15N1CD COG Use of Evidence-Based Supportive Care Clinical Practice Guidelines in Pediatric Oncology Pediatric CIRB
ACCL1633 COG The Effectiveness of Lactobacillus plantarum (LBP, IND #17339) In preventing Acute Graft-versus-Host Disease (GvHD) in Children undergoing Alternative Hematopoietic Progenitor Cell Transplantation (HCT) Pediatric CIRB