Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| AALL0331 | COG | Standard Risk B-precursor Acute Lymphoblastic Leukemia (ALL): A Phase III Group-Wide Study | Pediatric CIRB | Completed | |
| AALL03B1 | COG | Classification of Acute Lymphoblastic Leukemia | Pediatric CIRB | Completed | |
| AALL03N1 | COG | Understanding the Ethnic and Racial Differences in Survival in Children with Acute Lymphoblastic Leukemia | Pediatric CIRB | Completed | |
| AALL0433 | COG | Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies. A Groupwide Phase III Study | Pediatric CIRB | Completed | |
| AALL0434 | COG | Intensified Methotrexate; Nelarabine (Compound 506U78; IND # 52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL) or T-cell Lymphoblastic Lymphoma: A Groupwide Phase III Study | Pediatric CIRB | Available to Open | |
| AALL05B1 | COG | A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens | Pediatric CIRB | Completed | |
| AALL0622 | COG | Intensified Tyrosine Kinase Inhibitor Therapy (Dasatinib: IND# 73969; NSC# 732517) in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (ALL): A Groupwide Phase II/III Study | Pediatric CIRB | Completed | |
| AALL0631 | COG | A Phase III Study of Risk Directed Therapy for Infants with Acute Lymphoblastic Leukemia (ALL): Randomization of Highest Risk Infants to Intensive Chemotherapy FLT3 Inhibition (CEP-701; Lestaurtinib; IND#76431; NSC#617807) | Pediatric CIRB | Available to Open | |
| AALL06N1 | COG | A Study of Neurocognitive Function in Children Treated for ALL: A Group-wide; Non-Therapeutic Companion Study to AALL0232 | Pediatric CIRB | Completed | |
| AALL07P1 | COG | A Phase II Pilot Trial of Bortezomib (PS-341; Velcade; IND# 58;443) in Combination with Intensive Re-Induction Therapy for Children with Relapsed Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphoma (LL) | Pediatric CIRB | Completed |