Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number Sort descending | Lead Group | Study Title | CIRB | Study Status | |
|---|---|---|---|---|---|
| S2210 | SWOG | A Phase II Study of Neoadjuvant Carboplatin for Localized, High Risk Prostate Cancer with Germline BRCA1/2 Mutations | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2212 | SWOG | Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2213 | SWOG | A Phase III, Randomized Study of Daratumumab, Cyclophosphamide, Bortezomib and Dexamethasone (Dara-VCD) Induction Followed by Autologous Stem Cell Transplant or Dara-VCD Consolidation and Daratumumab Maintenance in Patients with Newly Diagnosed AL Amyloidosis | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2302 | SWOG | Pragmatica - Lung: A Prospective Randomized Study of Ramucirumab (LY3009806; NSC 749128) plus Pembrolizumab (MK-3475; NSC 776864) versus Standard of Care (SOC) for Participants Previously Treated with Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2303 | SWOG | Randomized Phase II/III Trial of 2nd Line Nivolumab + Paclitaxel + Ramucirumab versus Paclitaxel + Ramucirumab in Patients with PD-L1 CPS ≥ 1 Advanced Gastric and Esophageal Adenocarcinoma (PARAMUNE) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2308 | SWOG | Randomized Phase III Study of Mosunetuzumab vs. Rituximab for Low Tumor Burden Follicular Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2312 | SWOG | A Phase III Study of Cabazitaxel with or without Carboplatin in Patients with Metastatic Castrate Resistant Prostate Cancer (MCRPC), Stratified by Aggressive Variant Signature | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S2408 | SWOG | A Randomized Phase III Blinded Trial of Lanreotide for the Prevention of Postoperative Pancreatic Fistula | Cancer Prevention and Control CIRB | Available to Open | |
| S2414 | SWOG | Randomized Phase III Trial INcorporating Pathologic Complete ReSponse in Participants with Early StaGe Non-Small Cell Lung Cancer to Optimize ImmunotHerapy in the AdjuvanT Setting (INSIGHT) | Adult CIRB - Late Phase Emphasis | Available to Open | |
| S9910 | SWOG | Leukemia Centralized Reference Laboratories and Tissue Repositories Ancillary | Adult CIRB - Late Phase Emphasis | Completed |