CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ANBL0931 | COG | A Comprehensive Safety Trial of Chimeric Antibody 14.18 (ch14.18) with GM-CSF, IL-2 and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy | Pediatric CIRB | Completed |
| S0106 | SWOG | A Phase III Study of the Addition of Gemtuzumab Ozogamicin (Mylotarg) during Induction Therapy Versus Standard Induction with Daunomycin and Cytosine Arabinoside Followed by Consolidation and Subsequent Randomization to Post-Consolidation Therapy with Gemtuzumab Ozogamicin (Mylotarg) or No Additional Therapy for Patients Under Age 61 with Previously Untreated De Novo Acute Myeloid Leukemia (AML) | Adult CIRB - Late Phase Emphasis | Completed |
| E2902 | ECOG | A Phase III Randomized Study of Farnesyl Transferase Inhibitor R115777 in Acute Myeloid Leukemia (AML) Patients in Second or Subsequent Remission or in Remission After Primary Induction Failure or Patients over Age 60 in First Remission | Adult CIRB - Late Phase Emphasis | Completed |
| WF-1803CD | NCORP-Wake Forest University | Supportive Care Service Availability for Cancer Caregivers in Community Oncology Practices | Cancer Prevention and Control CIRB | Completed |
| S0518 | SWOG | Phase III Prospective Randomized Comparison of Depot Octreotide plus Interferon Alpha versus Depot Octreotide plus Bevacizumab (NSC #704865) in Advanced; Poor Prognosis Carcinoid Patients | Adult CIRB - Late Phase Emphasis | Completed |
| ARST03P1 | COG | A Pilot Phase II Study for Children with Infantile Fibrosarcoma | Pediatric CIRB | Completed |
| AEPI05N1 | COG | Carcinogen Metabolism; DNA Repair; Parental Exposures and Retinoblastoma: A Groupwide Non-Therapeutic Study | Pediatric CIRB | Completed |
| NCIC-MA.32 | NCIC CTG | A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| AAML05P1 | COG | Killer Immunoglobulin-like Receptor (KIR) Incompatible Unrelated Donor Hematopoietic Stem Cell Transplantation (SCT) for AML with Monosomy 7; -5/5q-; High FLT3-ITD AR; or Refractory and Relapsed Acute Myelogenous Leukemia (AML) in Children: A Children's Oncology Group (COG) Study (A Groupwide Pilot Study) | Pediatric CIRB | Completed |
| 9925 | ETCTN | Phase II Trial of Nivolumab for HTLV-Associated Adult T Cell Leukemia/Lymphoma | Adult CIRB - Early Phase Emphasis | Completed |