CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 10608 | ETCTN | A Phase II Trial of Durvalumab with Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma | Adult CIRB - Early Phase Emphasis | Completed |
| 10605 | ETCTN | A Phase 1 Study of ZEN003694 (ZEN-3694) in Combination with Cetuximab and Encorafenib in Patients with Refractory BRAF V600E Metastatic Colorectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10603 | ETCTN | A Phase 2 Study of M1774 in Refractory SPOP-mutant Prostate Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10601 | ETCTN | A Phase 1 Study of Mosunetuzumab with Polatuzumab Vedotin and Lenalidomide (M+Pola+Len) in Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL) | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10597 | ETCTN | A Phase 1 Study of APG-1252 (pelcitoclax) and cobimetinib in recurrent ovarian and endometrial cancers | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10596 | ETCTN | A Phase 1b Study of Menin Inhibitor SNDX-5613 in Combination with Daunorubicin and Cytarabine in Newly Diagnosed Patients with Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype with Higher-Risk Features or MLL/KMT2A Rearranged Disease | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10592 | ETCTN | A Randomized Phase 2 Study of ATR inhibition in advanced PD-(L)1-refractory Merkel cell carcinoma: The MATRiX Trial | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10590 | ETCTN | NORM: Nodular Lymphocyte-predominant Hodgkin Lymphoma Patients Treated in a Randomized Phase 2 Trial with Either Rituximab or Mosunetuzumab | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10579 | ETCTN | Phase I trial of ZEN003694 (ZEN-3694) in combination with capecitabine in patients with solid tumors | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10577 | ETCTN | Pilot Study of CBX-12 Pharmacodynamics in Patients with Advanced Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open |