CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| GOG-0249 | GOG | A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed By Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk; Early Stage Endometrial Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| 9878 | ETCTN | A Phase 1/2 Trial of Erlotinib and Onalespib lactate in EGFR-Mutant Non-Small Cell Lung Cancer | Adult CIRB - Early Phase Emphasis | Completed |
| ARAR0331 | COG | Treatment of Childhood Nasopharyngeal Carcinoma with Neoadjuvant Chemotherapy and Concomitant Chemoradiotherapy: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| AALL08P1 | COG | Intensified PEG-Asparaginase in High Risk Acute Lymphoblastic Leukemia (ALL): A Pilot Study | Pediatric CIRB | Completed |
| NSABP-C-08 | NSABP | A Phase III Clinical Trial Comparing Infusional 5-Fluorouracil (5-FU); Leucovorin; and Oxaliplatin (mFOLFOX6) Every Two Weeks with Bevacizumab to the Same Regimen without Bevacizumab for the Treatment of Patients with Resected Stages II and III Carcinoma of the Colon | Adult CIRB - Late Phase Emphasis | Completed |
| S1513 | SWOG | Randomized Phase II Study of 2nd Line FOLFIRI Versus Modified FOLFIRI with PARP Inhibitor ABT-888 (Veliparib) (NSC-737664) in Metastatic Pancreatic Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| 10249 | ETCTN | MLN9708 (Ixazomib) and MLN4924 (Pevonedistat) in Relapsed/Refractory Multiple Myeloma Patients: A Phase 1b Trial | Adult CIRB - Early Phase Emphasis | Completed |
| ANBL0532 | COG | Phase III Randomized Trial of Single vs. Tandem Myeloablative Consolidation Therapy for High-Risk Neuroblastoma: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| AOST06P1 | COG | Feasibility and Dose Discovery Analysis of Zoledronic Acid with Concurrent Chemotherapy in the Treatment of Newly Diagnosed Metastatic Osteosarcoma: A Groupwide Pilot Study | Pediatric CIRB | Completed |
| ACCL05C1 | COG | A Group-Wide; Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy | Pediatric CIRB | Completed |