CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S0334 | SWOG | Myeloma Specimen Repository Protocol Ancillary | Adult CIRB - Late Phase Emphasis | Completed |
| MAY2017-09-01 | CP-CTNet_CLO-Mayo Clinic | Phase I Double-Blind, Placebo-Controlled Trial of 27 mg Dolcanatide (SP-333) to Demonstrate Colorectal Bioactivity in Healthy Volunteers | Cancer Prevention and Control CIRB | Completed |
| CALGB-90401 | CALGB | A Randomized Double-Blinded Placebo Controlled Phase III Trial Comparing Docetaxel and Prednisone with and without Bevacizumab (IND #7921; NSC #704865) in Men with Hormone Refractory Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| S1300 | SWOG | A Randomized; Phase II Trial of Crizotinib Plus Pemetrexed Versus Pemetrexed Monotherapy in ALK-Positive Non-Squamous NSCLC Patients Who Have Progressed Systematically After Previous Clinical Benefit From Crizotinib Monotherapy<br> | Adult CIRB - Early Phase Emphasis | Completed |
| ACCL04C2 | COG | Randomized Study of Electroacupuncture Treatment for Delayed Chemotherapy-induced Nausea and Vomiting in Patients with Pediatric Solid Tumors 02-AT-0172 | Pediatric CIRB | Completed |
| CALGB-40502 | CALGB | A Randomized Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound Nab-Paclitaxel or Ixabepilone With or Without Bevacizumab as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer<br> | Adult CIRB - Late Phase Emphasis | Completed |
| E1105 | ECOG | A Randomized Phase III Double-Blind Placebo-Controlled Trial of First-line Chemotherapy and Trastuzumab with or without Bevacizumab for Patients with HER-2/NEU Over-expressing Metastatic Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| 9875 | ETCTN | Phase 2 Study of AT13387 (onalespib) in ALK+ ALCL; MCL; and BCL-6+ DLBCL | Adult CIRB - Early Phase Emphasis | Completed |
| GOG-0212 | GOG | A Randomized Phase III Trial of Maintenance Chemotherapy Comparing 12 Monthly Cycles of Single Agent Paclitaxel or CT-2103 (IND# 70177) Versus No Treatment Until Documented Relapse in Women With Advanced Ovarian; Primary Peritoneal; or Fallopian Tube Cancer who Achieve a Complete Clinical Response to Primary Platinum/Taxane Chemotherapy | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0275 | GOG | A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia | Adult CIRB - Late Phase Emphasis | Completed |