CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A071701 | Alliance | Genomically-Guided Treatment Trial in Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071601 | Alliance | Phase II Trial of BRAF/MEK Inhibitors in Papillary Craniopharyngiomas | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071401 | Alliance | Phase II Trial of SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas with SMO/AKT/NF2/CDK Pathway Mutations | Adult CIRB - Early Phase Emphasis | Available to Open |
| A071102 | Alliance | A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation | Adult CIRB - Late Phase Emphasis | Available to Open |
| A062102 | Alliance | Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients | Adult CIRB - Late Phase Emphasis | Available to Open |
| A061402 | Alliance | Solitary Plasmacytoma of Bone: Randomized Phase III Trial to Evaluate Treatment with Adjuvant Systemic Treatment and Zoledronic Acid Versus Zoledronic Acid After Definite Radiation Therapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| A052101 | Alliance | A Randomized Phase 3 Trial of Continuous vs Intermittent Maintenance Therapy with Zanubrutinib as Upfront Treatment in Older Patients with Mantle Cell Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| A051902 | Alliance | A Randomized Phase II Study of CHO(E)P vs CC-486-CHO(E)P vs Duvelisib-CHO(E)P in Previously Untreated CD30 Negative Peripheral T-Cell Lymphomas | Adult CIRB - Late Phase Emphasis | Available to Open |
| A051901 | Alliance | Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab (NIVO-MR2) Induction Followed by Lenalidomide and Nivolumab Maintenance in Primary CNS Lymphoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| A051701 | Alliance | Randomized Phase II/III Study of Venetoclax (ABT 199) Plus Chemoimmunotherapy for MYC/BCL2 Double-Hit and Double-Expressing Lymphomas | Adult CIRB - Late Phase Emphasis | Available to Open |