CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| E4402 | ECOG | Randomized Phase III Trial Comparing Two Different Rituximab Dosing Regimens for Patients with Low Tumor Burden Indolent Non-Hodgkin's Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| 9676 | ETCTN | A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10590 | ETCTN | NORM: Nodular Lymphocyte-predominant Hodgkin Lymphoma Patients Treated in a Randomized Phase 2 Trial with Either Rituximab or Mosunetuzumab | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-HN005 | NRG | A Randomized Phase II/III Trial of De-intensified Radiation Therapy for Patients with Early-Stage, p16-Positive, Non-Smoking Associated Oropharyngeal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| ACNS1831 | COG | A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG) | Pediatric CIRB | Available to Open |
| RTOG-0924 | RTOG | Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| CALGB-140503 | CALGB | A Phase III Randomized Trial of Lobectomy versus Sublobar Resection for Small (= 2 Cm) Peripheral Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10139 | ETCTN | A Randomized Phase 2 Study of Atezolizumab in Combination with Cobimetinib versus Atezolizumab Monotherapy in Participants with Unresectable Cholangiocarcinoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| WF-30917CD | NCORP-Wake Forest University | A Stepped-Care Telehealth Approach to Treat Distress in Rural Cancer Survivors | Cancer Prevention and Control CIRB | Available to Open |
| EA6194 | ECOG-ACRIN | Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination with CMP-001 in Patients with Operable Melanoma: Efficacy and Biomarker Study | Adult CIRB - Late Phase Emphasis | Available to Open |