CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A071702 | Alliance | A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| A031902 | Alliance | CASPAR - A Phase III Trial of Enzalutamide and Rucaparib as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| AREN03B2 | COG | Renal Tumors Classification; Biology; and Banking Study | Pediatric CIRB | Available to Open |
| AAML1331 | COG | A Phase III Study for Patients with Newly Diagnosed Acute Promyelocytic Leukemia (APL) using Arsenic Trioxide and All-Trans Retinoic Acid: A COG Groupwide Phase III Study | Pediatric CIRB | Available to Open |
| E4402 | ECOG | Randomized Phase III Trial Comparing Two Different Rituximab Dosing Regimens for Patients with Low Tumor Burden Indolent Non-Hodgkin's Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| AAML1531 | COG | Risk-stratified Therapy for Acute Myeloid Leukemia in Down Syndrome: A COG Groupwide Phase III Study | Pediatric CIRB | Available to Open |
| EA9152 | ECOG-ACRIN | A Phase Ib/II Study of Venetoclax (ABT-199) in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia | Adult CIRB - Late Phase Emphasis | Available to Open |
| A221505 | Alliance | RT Charm: Phase III Randomized Trial of Hypofractionated Post Mastectomy Radiation with Breast Reconstruction | Cancer Prevention and Control CIRB | Available to Open |
| ARST2032 | COG | A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma | Pediatric CIRB | Available to Open |
| A022101 | Alliance | A Pragmatic Randomized Phase III Trial Evaluating Total Ablative Therapy for Patients with Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur) | Adult CIRB - Late Phase Emphasis | Available to Open |