Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|A071701||Alliance||Genomically-Guided Treatment Trial in Brain Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|A011106||Alliance||ALTernate approaches for clinical stage II or III Estrogen Receptor positive breast cancer NeoAdjuvant TrEatment (ALTERNATE) in postmenopausal women: A Phase III Study||Adult CIRB - Late Phase Emphasis||Available to Open|
|A031702||Alliance||A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)||Adult CIRB - Late Phase Emphasis||Available to Open|
|A071801||Alliance||Phase III Trial of Post-Surgical Single Fraction Stereotactic Radiosurgery (SRS) Compared with Fractionated SRS (FSRS) for Resected Metastatic Brain Disease||Adult CIRB - Late Phase Emphasis||Available to Open|
|A191901||Alliance||Optimizing Endocrine Therapy Through Motivational Interviewing and Text Interventions||Cancer Prevention and Control CIRB||Available to Open|
|A091903||Alliance||A Randomized Phase II Trial of Adjuvant Nivolumab with or Without Cabozantinib in Patients with Resected Mucosal Melanoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|A071102||Alliance||A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation||Adult CIRB - Late Phase Emphasis||Available to Open|
|A221405||Alliance||A Study Evaluating the Pregnancy Outcomes and Safety of Interrupting Endocrine Therapy for Young Women with Endocrine Responsive Breast Cancer who Desire Pregnancy||Cancer Prevention and Control CIRB||Available to Open|
|A211801||Alliance||BRCA-P: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, International Phase 3 Study to Determine the Preventive Effect of Denosumab on Breast Cancer in Women Carrying a BRCA1 Germline Mutation||Cancer Prevention and Control CIRB||Available to Open|
|A031102||Alliance||A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel; Ifosfamide; and Cisplatin (TIP) with High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors||Adult CIRB - Late Phase Emphasis||Available to Open|