CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S1714 | SWOG | A Prospective Observational Cohort Study to Develop a Predictive Model of Taxane-Induced Peripheral Neuropathy in Cancer Patients | Cancer Prevention and Control CIRB | Available to Open |
| UMI21-05-01 | CP-CTNet_LAO-University of Michigan | Obeticholic Acid for Prevention in Barrett’s Esophagus | Cancer Prevention and Control CIRB | Available to Open |
| A071701 | Alliance | Genomically-Guided Treatment Trial in Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |
| A021804 | Alliance | A Prospective, Multi-Institutional Phase II Trial Evaluating Temozolomide vs Temozolomide and Olaparib for Advanced Pheochromocytoma and Paraganglioma | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10358 | ETCTN | Phase 1/1B study of DS-8201a in combination with ATR Inhibition (AZD6738) in advanced solid tumors with HER2 expression (DASH Trial) | Adult CIRB - Early Phase Emphasis | Available to Open |
| CALGB-40601 | CALGB | Randomized Phase III Trial of Paclitaxel + Trastuzumab + Lapatinib Versus Paclitaxel + Trastuzumab as Neoadjuvant Treatment of HER2-Positive Primary Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A032002 | Alliance | Phase II Randomized Trial of Atezolizumab versus Atezolizumab and Radiation Therapy for Platinum Ineligible/Refractory Metastatic Urothelial Cancer (ART) | Adult CIRB - Late Phase Emphasis | Available to Open |
| WF-2202 | NCORP-Wake Forest University | Optimizing Psychosocial Intervention for Breast Cancer-related Sexual Morbidity: The Sexual Health and Intimacy Education (SHINE) Trial | Cancer Prevention and Control CIRB | Available to Open |
| AEWS1031 | COG | A Phase III Randomized Trial of Adding Vincristine-topotecan-cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma: A Groupwide Phase III Study | Pediatric CIRB | Available to Open |
| 9767 | ETCTN | An Open Label; Multicenter; Single arm Phase II study to evaluate the Activity and Tolerability of the novel mTOR Inhibitor; MLN0128 (TAK-228); in patients with Locally Advanced or Metastatic Transitional Cell Carcinoma of the urothelial tract whose tumors harbor a TSC1 and/or a TSC2 mutation | Adult CIRB - Early Phase Emphasis | Available to Open |