CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ACCL0431 | COG | A Randomized Phase III Study of Sodium Thiosulfate (IND#72877; NSC#45624) for the Prevention of Cisplatin-Induced Ototoxicity in Children: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| A191402CD | Alliance | Testing Decision Aids to Improve Prostate Cancer Decisions for Minority Men | Cancer Prevention and Control CIRB | Completed |
| 9571 | ETCTN | A phase IB study of the combination of AZD6244 hydrogen sulfate (selumetinib) and cyclosporin A (CsA) in patients with advanced solid tumors with an expansion cohort in metastatic colorectal cancer | Adult CIRB - Early Phase Emphasis | Completed |
| CALGB-90601 | CALGB | A Randomized Double-Blinded Phase III Study Comparing Gemcitabine; Cisplatin; and Bevacizumab to Gemcitabine; Cisplatin; and Placebo in Patients with Advanced Transitional Cell Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| S1203 | SWOG | A Randomized Phase III Study of Standard Cytarabine plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) versus IA with Vorinostat (NSC-701852) (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML) | Adult CIRB - Late Phase Emphasis | Completed |
| ACOSOG-Z4099 | ACSOG | A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)<br><br> | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GY002 | NRG | A Phase II Evaluation of Nivolumab; a Fully Human Antibody against PD-1; in the Treatment of Persistent or Recurrent Cervical Cancer | Adult CIRB - Early Phase Emphasis | Completed |
| ARST0431 | COG | Intensive Multi-Agent Therapy; Including Dose-Compressed Cycles of Ifosfamide/Etoposide (IE) and Vincristine/Doxorubicin/Cyclophosphamide (VDC) for Patients with High-Risk Rhabdomyosarcoma: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| ADVL0524 | COG | Phase II Trial of Ixabepilone (BMS-247550); an Epothilone B Analog; in Children and Young Adults with Refractory Solid Tumors | Pediatric CIRB | Completed |
| ANHL1131 | COG | Intergroup Trial for Children or Adolescents with B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients | Pediatric CIRB | Completed |