CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| GOG-0275 | GOG | A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia | Adult CIRB - Late Phase Emphasis | Completed |
| MDA2017-09-03 | CP-CTNet_CLO-MD Anderson | Pilot Study of Denosumab in BRCA1/2 Mutation Carriers scheduled for Risk-reducing Salpingooophorectomy | Cancer Prevention and Control CIRB | Completed |
| ADVL0221 | COG | A Phase II Study of Trabectedin (ET-743; Yondelis) in Children with Recurrent Rhabdomyosarcoma; Ewing Sarcoma; or Nonrhabdomyosarcomatous Soft Tissue Sarcomas | Pediatric CIRB | Completed |
| E3999 | ECOG | A Randomized; Placebo-controlled; Double Blind; Trial of the Administration of the MDR Modulator; Zosuquidar Trihydrochloride (LY335979); During Conventional Induction and Post-Remission Therapy in Patients Greater than 60 Years of Age with Newly Diagnosed Acute Myeloid Leukemia; Refractory Anemia with Excess Blasts in Transformation or High-Risk Refractory Anemia with Excess Blasts | Adult CIRB - Late Phase Emphasis | Completed |
| 9653 | ETCTN | Phase II Trial of Gemcitabine-Eribulin (GE) in Cisplatin Ineligible Patients with Advanced or Unresectable Unrothelial Carcinoma of the Bladder | Adult CIRB - Early Phase Emphasis | Completed |
| RTOG-0129 | RTOG | A Phase III Trial of Concurrent Radiation and Chemotherapy (Followed by Surgery for Residual Primary/N2-3 Nodal Disease) for Advanced Head and Neck Carcinomas | Adult CIRB - Late Phase Emphasis | Completed |
| S0226 | SWOG | Phase III Randomized Trial of Anastrozole Versus Anastrozole and Fulvestrant as First Line Therapy for Post Menopausal Women with Metastatic Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| AALL07P4 | COG | A Pilot Study of Intravenous EZN-2285 (SC-PEG E. coli L-asparaginase; IND# 100594) or Intravenous Oncaspar in the Treatment of Patients with High-Risk Acute Lymphoblastic Leukemia (ALL): A Limited Institution Pilot Study | Pediatric CIRB | Completed |
| PEPN21EHR/PBTC-N15 | Pediatric CITN | Pilot Study to Enable Electronic Laboratory Data Transfer into Medidata Rave | Pediatric CIRB | Completed |
| A021302 | Alliance | Impact of Early FDG-PET Directed Intervention on Preoperative Therapy for Locally Advanced Gastric Cancer: A Random Assignment Phase II Study | Adult CIRB - Early Phase Emphasis | Completed |