CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 10382 | ETCTN | A Phase I/II Trial Evaluating the Safety and Efficacy of Eribulin in Combination with Copanlisib in Patients with Metastatic Triple Negative Breast Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10384 | ETCTN | A Phase 1b/2 Study of Hu5F9-G4 (magrolimab) in Combination with Mogamulizumab in Relapsed/Refractory Treated T- cell Lymphoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10387 | ETCTN | Pilot Trial of Nivolumab plus Cabozantinib for Advanced Solid Tumors in Patients with HIV infection | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10388 | ETCTN | A Phase I Trial of Triapine and Lutetium Lu 177 Dotatate in Combination for Well-Differentiated Somatostatin Receptor-Positive Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10389 | ETCTN | A Phase 1 Trial Combining WEE1 Inhibitor Adavosertib (AZD1775) with Radiation Therapy for Metastatic or Inoperable and Ineligible for Definitive Chemoradiation Esophageal and Gastroesophageal Junction Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10398 | ETCTN | A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell Sarcoma | Adult CIRB - Early Phase Emphasis | Completed |
| 10399 | ETCTN | A Phase 1 Study of Entinostat in Combination with Atezolizumab / Carboplatin / Etoposide in Previously Untreated Extensive-Stage Small Cell Lung Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10401 | ETCTN | A Phase 0 window-of-opportunity pharmacodynamic trial of triapine (NSC# 663249) in uterine corpus serous adenocarcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10402 | ETCTN | BAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (PDA) | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10403 | ETCTN | Phase 1 Trial of Gemcitabine Combined with the BAY 1895344 ATR Inhibitor with Expansion Cohorts in Advanced Pancreatic and Ovarian Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |