CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S2207 | SWOG | Randomized Phase II Study of the Addition of Targeted Therapeutic Agents to Tafasitamab-Based Therapy in Non-Transplant-Eligible Patients with Relapsed/Refractory Large B-Cell Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| 9706 | ETCTN | Randomized phase II study to assess the role of Nivolumab as single agent to eliminate minimal residual disease and maintain remission in acute myelogenous leukemia (AML) patients after chemotherapy (REMAIN Trial) | Adult CIRB - Early Phase Emphasis | Available to Open |
| A221208 | Alliance | Randomized Phase II Study: Corticosteroids and Bevacizumab vs. Corticosteroids and Placebo (BeSt) for Radionecrosis after Radiosurgery for Brain Metastases | Cancer Prevention and Control CIRB | Available to Open |
| S1608 | SWOG | Randomized Phase II Trial in Early Relapsing or Refractory Follicular Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-LU001 | NRG | Randomized Phase II Trial of Concurrent Chemoradiotherapy +/- Metformin HCL in Locally Advanced NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2107 | SWOG | Randomized Phase II Trial of Encorafenib and Cetuximab with or without Nivolumab (NSC #748726) for Patients with Previously Treated, Microsatellite Stable, BRAFV600E Metastatic and/or Unresectable Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2011 | SWOG | Randomized Phase II Trial of Gemcitabine, Avelumab and Carboplatin vs. No Neoadjuvant Therapy Preceding Surgery for Cisplatin-Ineligible Muscle-Invasive Urothelial Carcinoma: SWOG GAP Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-BN001 | NRG | Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation With Concomitant and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| A021901 | Alliance | Randomized Phase II Trial of Lutetium Lu 177 Dotatate versus Everolimus in Somatostatin Receptor Positive Bronchial Neuroendocrine Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU007 | NRG | Randomized Phase II Trial of Niraparib with Standard Combination Radiotherapy and Androgen Deprivation Therapy (ADT) in High Risk Prostate Cancer (with Initial Phase I) | Adult CIRB - Late Phase Emphasis | Available to Open |