CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| CALGB-80203 | CALGB | A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with and without Cetuximab (C225) for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum | Adult CIRB - Late Phase Emphasis | Completed |
| EAQ152 | ECOG-ACRIN | A Randomized Study of Pre-disclosure Genetic Education v. Usual Care in Tumor Profiling for Advanced Cancer and a Pilot Study of Remote Genetic Counseling for Participants with Potential Germline Mutations Identified on Tumor Profiling | Adult CIRB - Early Phase Emphasis | Completed |
| S0500 | SWOG | A Randomized Phase III Trial to Test the Strategy of Changing Therapy Versus Maintaining Therapy for Metastatic Breast Cancer Patients Who Have Elevated Circulating Tumor Cell Levels at First Follow-Up Assessment | Adult CIRB - Late Phase Emphasis | Completed |
| ACNS0821 | COG | Temozolomide with Irinotecan versus Temozolomide; Irinotecan plus Bevacizumab (NSC# 704865; BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood; A COG Randomized Phase II Screening Trial: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| NRG-CC006 | NRG | A Survey Study to Evaluate Physician Attitudes and Perceptions Regarding a Non-Surgical Approach to Breast Cancer Treatment | Cancer Prevention and Control CIRB | Completed |
| CALGB-30607 | CALGB | Randomized; Phase III; Double-Blind Placebo-Controlled Trial of Sunitinib (NSC #736511; IND #74019) as Maintenance Therapy in Non-Progressing Patients Following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced; Stage IIIB/IV Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| EAQ201 | ECOG-ACRIN | COVID-19 Related Financial Hardship and Distress in Women Who Decline TMIST (EA1151) Participation | Cancer Prevention and Control CIRB | Completed |
| MAY2016-07-01F | CP-CTNet_CLO-Mayo Clinic | Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01 Weekly Erlotinib for Familial Adenomatous Polyposis | Cancer Prevention and Control CIRB | Completed |
| S0012 | SWOG | A Comparative Randomized Study of Standard Doxorubicin and Cyclophosphamide Followed by Weekly Paclitaxel Vs. Weekly Doxorubicin and Daily Oral Cyclophosphamide Plus G-CSF Followed by Weekly Paclitaxel as Neoadjuvant Therapy for Inflammatory and Locally Advanced Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| AAML0121 | COG | "A Phase II Study of Amifostine In Children with Myelodysplastic Syndrome: A Group-wide Study" | Pediatric CIRB | Completed |