CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ANBL0421 | COG | A Phase II Study of Irinotecan + Temozolomide in Children with Recurrent Neuroblastoma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| TRC-10446 | NCI | Tocilizumab in Hospitalized Cancer Patients with Coronavirus 2019 (SARS-CoV-2) and Severe Complications of Coronavirus Disease 19 (COVID-19) | Adult CIRB - Late Phase Emphasis | Completed |
| NSABP-B-38 | NSABP | A Phase III; Adjuvant Trial Comparing Three Chemotherapy Regimens in Women with Node-Positive Breast Cancer: Docetaxel/Doxorubicin/Cyclophosphamide (TAC); Dose-Dense (DD) Doxorubicin/Cyclophosphamide Followed by DD Paclitaxel (DD AC->P); DD AC Followed by DD Paclitaxel Plus Gemcitabine (DD AC->PG) | Adult CIRB - Late Phase Emphasis | Completed |
| UWI2016-07-01 | CP-CTNet_CLO-University of Wisconsin | Phase IIB Randomized, Placebo-Controlled Trial of ACTOplus met® XR in Subjects with Stage I-IV Squamous Cell Carcinoma of the Oral Cavity or Oropharynx Prior to Definitive Treatment | Cancer Prevention and Control CIRB | Completed |
| EA1141 | ECOG-ACRIN | Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis in Breast Cancer Screening in Women with Dense Breasts | Cancer Prevention and Control CIRB | Completed |
| ACNS0621 | COG | Cilengitide (EMD 121974) (IND# 59073) in Recurrent or Progressive and Refractory Childhood High-Grade Glioma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| E5204 | ECOG | Intergroup Randomized Phase III Study of Postoperative Oxaliplatin; 5-Fluorouracil; and Leucovorin vs Oxaliplatin; 5-Fluorouracil; Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-Operative Chemoradiation | Adult CIRB - Late Phase Emphasis | Completed |
| 9925 | ETCTN | Phase II Trial of Nivolumab for HTLV-Associated Adult T Cell Leukemia/Lymphoma | Adult CIRB - Early Phase Emphasis | Completed |
| 10010 | ETCTN | A Phase 2 Study of Atezolizumab (MPDL3280A) in Combination with Bevacizumab in Patients with Recurrent; Persistent or Metastatic Cervical Cancer | Adult CIRB - Early Phase Emphasis | Completed |
| NCCTG-N06C6 | NCCTG | A Phase III Randomized Trial of Cryoablation vs. Radiation for the Palliation of Painful Bone Metastases | Adult CIRB - Late Phase Emphasis | Completed |