CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 9984 | ETCTN | A Randomized Phase 2 Study of cediranib in Combination with olaparib versus olaparib alone in men with metastatic castration resistant prostate cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10347 | ETCTN | A phase I study with an expansion cohort of duvelisib and nivolumab in mycosis fungoides (MF) and Sézary syndrome (SS) | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-HN009 | NRG | Randomized Phase II/III Trial of Radiation with High-Dose Cisplatin (100 mg/m2) Every Three Weeks Versus Radiation with Low-Dose Weekly Cisplatin (40 mg/m2) for Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN) | Adult CIRB - Late Phase Emphasis | Available to Open |
| E5103 | ECOG | A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide Followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1500 | SWOG | A Randomized; Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968]; Crizotinib [NSC #749005]; Savolitinib [NSC #785348]; and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET) | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10042 | ETCTN | A Phase II trial of AZD9291 (osimertinib) with or without bevacizumab in patients with EGFR mutation positive NSCLC and brain metastases | Adult CIRB - Early Phase Emphasis | Available to Open |
| RTOG-1112 | RTOG | Randomized Phase III Study of Sorafenib Versus Stereotactic Body Radiation Therapy Followed by Sorafenib in Hepatocellular Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| UWI2015-05-01 | CP-CTNet_CLO-University of Wisconsin | Phase Ib 9cUAB30 in Early Stage Breast Cancer to Evaluate Biologic Effect | Cancer Prevention and Control CIRB | Available to Open |
| EA6174 | ECOG-ACRIN | STAMP: Surgically Treated Adjuvant Merkel cell Carcinoma with Pembrolizumab, a Phase III Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10553 | ETCTN | A Phase 2 Study of Darolutamide in Combination with Leuprolide Acetate in Hormone-Therapy Naïve Recurrent and/or Metastatic Androgen Receptor (AR) Positive Salivary Gland Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |